CAS 7240-37-1|7-Aminoactinomycin D
Introduction：Basic information about CAS 7240-37-1|7-Aminoactinomycin D, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-Aminoactinomycin D | ||
|---|---|---|---|
| CAS Number | 7240-37-1 | Molecular Weight | 1270.432 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1400.8±65.0 °C at 760 mmHg |
| Molecular Formula | C62H87N13O16 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 801.0±34.3 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 7-aminoactinomycin D |
|---|---|
| Synonym | More Synonyms |
7-Aminoactinomycin D BiologicalActivity
| Description | 7-Aminoactinomycin D is a fluorescent DNA stain. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others |
| References | [1]. Wadkins RM, et al. Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA. Biochemistry. 1991 Oct 1;30(39):9469-78. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1400.8±65.0 °C at 760 mmHg |
| Molecular Formula | C62H87N13O16 |
| Molecular Weight | 1270.432 |
| Flash Point | 801.0±34.3 °C |
| Exact Mass | 1269.639404 |
| PSA | 386.00000 |
| LogP | -5.02 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.664 |
| InChIKey | YXHLJMWYDTXDHS-IYYIOUBUSA-N |
| SMILES | Cc1c2oc3c(C)c(N)cc(C(=O)NC4C(=O)NC(C(C)C)C(=O)N5CCCC5C(=O)N(C)CC(=O)N(C)C(C(C)C)C(=O)OC4C)c3nc-2c(C(=O)NC2C(=O)NC(C(C)C)C(=O)N3CCCC3C(=O)N(C)CC(=O)N(C)C(C(C)C)C(=O)OC2C)c(N)c1=O |
| Storage condition | 2-8°C |
| Water Solubility | chloroform: 1 mg/mL, clear, red |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 3 umol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,448,1983
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 3 umol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,448,1983
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300 |
| Precautionary Statements | Missing Phrase - N15.00950417 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T+: Very toxic; |
| Risk Phrases | R26/27/28;R36/37/38 |
| Safety Phrases | 26-28-36/37-45 |
| RIDADR | UN 3462 6 |
| WGK Germany | 3 |
| RTECS | AU1579000 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
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Synonyms
| 7-Aminodactinomycin |
| MFCD00077295 |
| 7AAD |
| 3H-Phenoxazine-1,9-dicarboxamide, 2,7-diamino-N,N-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4, 
6-dimethyl-3-oxo- |
| 2,7-Diamino-N,N'-bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| 7-Actinomycin C1 |
| 2,7-Diamino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| 3H-Phenoxazine-1,9-dicarboxamide, 2,7-diamino-N,N-bis[(6S,9R,10S,13R,18aS)-hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyc 
lohexadecin-10-yl]-4,6-dimethyl-3-oxo- |
| 7-amino-actinomycin-D |
| 2,7-diamino-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide |
| 7-amino-AMD |
| Actinomycin D,7-amino |
