CAS 3316-09-4|4-nitrocatechol
| Common Name | 4-nitrocatechol | ||
|---|---|---|---|
| CAS Number | 3316-09-4 | Molecular Weight | 155.108 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 358.2±32.0 °C at 760 mmHg |
| Molecular Formula | C6H5NO4 | Melting Point | 173-177 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 168.8±13.6 °C |
Names
| Name | 4-nitrocatechol |
|---|---|
| Synonym | More Synonyms |
4-nitrocatechol BiologicalActivity
| Description | 4-Nitrocatechol is a potent lipoxygenase inhibitor[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>5-Lipoxygenase |
| Target | Human Endogenous Metabolite Microbial Metabolite |
| References | [1]. Ewa Skrzypczak-Jankun, et al. Soybean lipoxygenase-3 in complex with 4-nitrocatechol. Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):613-5. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 358.2±32.0 °C at 760 mmHg |
| Melting Point | 173-177 °C(lit.) |
| Molecular Formula | C6H5NO4 |
| Molecular Weight | 155.108 |
| Flash Point | 168.8±13.6 °C |
| Exact Mass | 155.021851 |
| PSA | 86.28000 |
| LogP | 1.68 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.668 |
| InChIKey | XJNPNXSISMKQEX-UHFFFAOYSA-N |
| SMILES | O=[N+]([O-])c1ccc(O)c(O)c1 |
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2908999090 |
Customs
| HS Code | 2908999090 |
|---|---|
| Summary | 2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles32
More Articles| Effect of commercially available green and black tea beverages on drug-metabolizing enzymes and oxidative stress in Wistar rats. Food Chem. Toxicol. 70 , 120-7, (2014) The effect of commercially available green tea (GT) and black tea (BT) drinks on drug metabolizing enzymes (DME) and oxidative stress in rats was investigated. Male Wistar rats were fed a laboratory c... | |
| Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols. Org. Biomol. Chem. 13(13) , 3887-99, (2015) The green tea polyphenol epigallocatechin-3-gallate (EGCG) was reported to effectively antagonize the ability of Bortezomib (BZM) to induce apoptosis in cancer cells. This interaction was attributed t... | |
| Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation. Drug Metab. Dispos. 43(1) , 126-39, (2014) Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investig... |
Synonyms
| EINECS 222-009-0 |
| 1,2-Benzenediol, 4-nitro- |
| 1,2-dihydroxy-4-nitrobenzene |
| [14C]-4-Nitrocatechol |
| NITROCATECHOL (MIX OF ISOMERS) |
| 4-nitrocathecol |
| 3,4-dihydroxynitrobenzene |
| 4-Nitro-1,2-benzenediol |
| 4-nitrocatechol |
| 4-Nitrobenzol-1,2-diol |
| MFCD00007242 |
| 4-Nitropyrocatechol |
| 4-nitrobenzene-1,2-diol |
