CAS 63958-90-7|Thymic Factor trifluoroacetate salt
| Common Name | Thymic Factor trifluoroacetate salt | ||
|---|---|---|---|
| CAS Number | 63958-90-7 | Molecular Weight | 858.85300 |
| Density | 1.417 g/cm33 | Boiling Point | 1658.9ºC at 760 mmHg |
| Molecular Formula | C33H54N12O15 | Melting Point | / |
| MSDS | USA | Flash Point | 957.1ºC |
Names
| Name | serum thymic factor |
|---|---|
| Synonym | More Synonyms |
Thymic Factor trifluoroacetate salt BiologicalActivity
| Description | Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide. Serum thymic factor induces hyperalgesia. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor has anti-diabetic, analgesic and anti-inflammatory effects[1][2][3]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Dardenne M,et al. Role of thymulin or its analogue as a new analgesic molecule. Ann N Y Acad Sci. 2006 Nov;1088:153-63. [2]. Kohda Y, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28(11):2087-91. [3]. Mizutani M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83. |
Chemical & Physical Properties
| Density | 1.417 g/cm33 |
|---|---|
| Boiling Point | 1658.9ºC at 760 mmHg |
| Molecular Formula | C33H54N12O15 |
| Molecular Weight | 858.85300 |
| Flash Point | 957.1ºC |
| Exact Mass | 858.38300 |
| PSA | 451.86000 |
| Appearance of Characters | white |
| Index of Refraction | 1.575 |
| InChIKey | LIFNDDBLJFPEAN-BPSSIEEOSA-N |
| SMILES | CC(NC(=O)C1CCC(=O)N1)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)O |
| Storage condition | −20°C |
| Water Solubility | deionized water: soluble |
Safety Information
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Synonyms
| pyroglutamyl-alanyl-lysyl-seryl-glutaminyl-glycyl-glycyl-seryl-asparagine |
| Pyr-Ala-Lys-Ser-Asn-Gly-Gly-Ser-Gln |
| Nonathymulin |
| pyro-Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH |
| THYMIC FACTOR |
| PYR-ALA-LYS-SER-GLN-GLY-GLY-SER-ASN |
| Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH |
| pGlu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn |
| STF,SeruM ThyMic Factor,ThyMulin |
| GLP-ALA-LYS-SER-GLN-GLY-GLY-SER-ASN |
| STF |
| THYMIC FACTOR SERUM |
