CAS 6398-98-7|Amodiaquin dihydrochloride dihydrate

Introduction：Basic information about CAS 6398-98-7|Amodiaquin dihydrochloride dihydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Amodiaquin dihydrochloride dihydrate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	Amodiaquin dihydrochloride dihydrate
CAS Number	6398-98-7	Molecular Weight	464.81
Density	/	Boiling Point	535.4ºC at 760 mmHg
Molecular Formula	C₂₀H₂₂ClN₃O_.2H₂O_.2HCl	Melting Point	/
MSDS	ChineseUSA	Flash Point	277.6ºC

Names

Name	amodiaquine hydrochloride
Synonym	More Synonyms

Amodiaquin dihydrochloride dihydrate BiologicalActivity

Description	Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated.
Related Catalog	Signaling Pathways >>Epigenetics >>Histone MethyltransferaseResearch Areas >>Inflammation/Immunology

Description

Amodiaquine dihydrochloride dihydrate is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent.Target: histamine N-methyltransferaseAmodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine is generally well tolerated.

Related Catalog

Signaling Pathways >>Epigenetics >>Histone MethyltransferaseResearch Areas >>Inflammation/Immunology

Chemical & Physical Properties

Boiling Point	535.4ºC at 760 mmHg
Molecular Formula	C₂₀H₂₂ClN₃O_.2H₂O_.2HCl
Molecular Weight	464.81
Flash Point	277.6ºC
PSA	48.39000
LogP	6.85620
InChIKey	YVNAYSHNIILOJS-UHFFFAOYSA-N
SMILES	CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O.Cl.Cl.O.O

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles1

Inhibition of influenza virus replication by targeting broad host cell pathways.

PLoS ONE 9(10) , e110631, (2014)

Antivirals that are currently used to treat influenza virus infections target components of the virus which can mutate rapidly. Consequently, there has been an increase in the number of resistant stra...

Synonyms

UNII:K6PW2S574L

Amodiaquine hydrochloride USP24

Amodiaquin dihydrochloride dihydrate

AMODIAQUIN DIHYDROCHLORIDE DIHYDATE

MFCD00078857

Amodiaquin hydrochloride dihydrate

AMODIAQUIN HYDROCHLORIDE

AMODIAQUINE 2HCL DIHYDRATE

EINECS 200-706-0

Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride, hydrate (1:2:2)

AMODIAQUIN DIHYDROCHLORIDE

AMODIAQUINE HCL

4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol dihydrochloride dihydrate

AMODIAQUINE DIHYDROCHLORIDE

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