CAS 58801-34-6|CA 1001

Introduction：Basic information about CAS 58801-34-6|CA 1001, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. CA 1001 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles7
6. Synonyms

Common Name	CA 1001
CAS Number	58801-34-6	Molecular Weight	684.98700
Density	1g/cm3	Boiling Point	715.1ºC at 760mmHg
Molecular Formula	C₃₈H₇₂N₂O₈	Melting Point	/
MSDS	USA	Flash Point	386.3ºC

Names

Name	eth 1001
Synonym	More Synonyms

CA 1001 BiologicalActivity

Description	Calcium ionophore I (ETH 1001) is a selective Ca2+ ionophore for biological membranes. Calcium ionophore I can be used in Ca2+-selective microelectrodes that can be used for quantitative intracellular measurements of resting Ca2+-activities and of slowly changing Ca2+-levels[1][2].
Related Catalog	Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Others
References	[1]. T R Hinds, et al. The effect of ETH 1001 on ion fluxes across red blood cell membranes. Cell Calcium. 1985 Jun;6(3):265-79. [2]. D Ammann. Ca2+-selective microelectrodes. Cell Calcium. 1985 Apr;6(1-2):39-55.

Description

Calcium ionophore I (ETH 1001) is a selective Ca2+ ionophore for biological membranes. Calcium ionophore I can be used in Ca2+-selective microelectrodes that can be used for quantitative intracellular measurements of resting Ca2+-activities and of slowly changing Ca2+-levels[1][2].

Related Catalog

Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Others

References

[1]. T R Hinds, et al. The effect of ETH 1001 on ion fluxes across red blood cell membranes. Cell Calcium. 1985 Jun;6(3):265-79.

[2]. D Ammann. Ca2+-selective microelectrodes. Cell Calcium. 1985 Apr;6(1-2):39-55.

Chemical & Physical Properties

Density	1g/cm3
Boiling Point	715.1ºC at 760mmHg
Molecular Formula	C₃₈H₇₂N₂O₈
Molecular Weight	684.98700
Flash Point	386.3ºC
Exact Mass	684.52900
PSA	111.68000
LogP	7.64160
InChIKey	CJAONIOAQZUHPN-KKLWWLSJSA-N
SMILES	CCOC(=O)CCCCCCCCCCCN(C)C(=O)COC(C)C(C)OCC(=O)N(C)CCCCCCCCCCCC(=O)OCC
Storage condition	2-8°C

Safety Information

Personal Protective Equipment	Eyeshields;Gloves
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles7

Design, properties, and applications of neutral ionophores.

Meth. Enzymol. 56 , 439, (1979)

T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.

J. Immunol. 183 , 5685-93, (2010)

IL-17A and IL-17F regulate granulopoiesis and are produced by memory T cells. Rag1(-/-) recombinase-activating gene-deficient mice cannot produce mature T cells but maintain normal neutrophil counts. ...

Ca2+ transport mediated by a synthetic neutral Ca2+ -ionophore in biological membranes.

Biochim. Biophys. Acta 470 , 437, (1977)

The effect of a synthetic neutral ligand on the Ca2+ permeability of several biological membranes has been investigated. The ligand had been previously shown to possess Ca2+ -ionophoric activities in ...

Synonyms

EINECS 261-449-8

MFCD00042943

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