Introduction：Basic information about CAS 77-38-3|Chlorphenoxamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chlorphenoxamine |
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| CAS Number | 77-38-3 | Molecular Weight | 303.82600 |
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| Density | 1.093g/cm3 | Boiling Point | 383.7ºC at 760 mmHg |
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| Molecular Formula | C18H22ClNO | Melting Point | / |
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| MSDS | / | Flash Point | 185.9ºC |
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Names
| Name | 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine |
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| Synonym | More Synonyms |
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Chlorphenoxamine BiologicalActivity
| Description | Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Histamine ReceptorSignaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Neurological Disease |
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Chemical & Physical Properties
| Density | 1.093g/cm3 |
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| Boiling Point | 383.7ºC at 760 mmHg |
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| Molecular Formula | C18H22ClNO |
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| Molecular Weight | 303.82600 |
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| Flash Point | 185.9ºC |
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| Exact Mass | 303.13900 |
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| PSA | 12.47000 |
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| LogP | 4.18170 |
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| Index of Refraction | 1.551 |
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| InChIKey | KKHPNPMTPORSQE-UHFFFAOYSA-N |
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| SMILES | CN(C)CCOC(C)(c1ccccc1)c1ccc(Cl)cc1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- KR3185000
- CHEMICAL NAME :
- Ethylamine, 2-(1-(p-chlorophenyl)-1-phenylethoxy)-N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 77-38-3
- BEILSTEIN REFERENCE NO. :
- 2057618
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H22-Cl-N-O
- MOLECULAR WEIGHT :
- 303.86
- WISWESSER LINE NOTATION :
- GR DX1&R&O2N1&1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 376 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2922199090 |
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Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Clorfenossamina [DCIT] |
| 2-(1-(4-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethanamine |
| Chlorphenoxamine [INN:BAN] |
| Clorfenoxamina [INN-Spanish] |
| {2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin |
| {2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine |
| Chlorphenoxaminum [INN-Latin] |
| Contristamine |
| Chlorphenoxamine |
