CAS 81123-06-0|Gastrin I rat
| Common Name | Gastrin I rat | ||
|---|---|---|---|
| CAS Number | 81123-06-0 | Molecular Weight | 2126.28000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C94H128N22O31S2 | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | pyr-arg-pro-pro-met-glu-glu-glu-glu-glu-ala-tyr-gly-trp-met-asp-phe-nh2 |
|---|---|
| Synonym | More Synonyms |
Gastrin I rat BiologicalActivity
| Description | Gastrin-1, rat (Rat Gastrin-17) is a peptide hormone, and can stimulate gastric acid secretion potently[1]. |
|---|---|
| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Cholecystokinin Receptor |
| References | [1]. Copps J, et, al. The production and role of gastrin-17 and gastrin-17-gly in gastrointestinal cancers. Protein Pept Lett. 2009; 16(12): 1504-18. |
Chemical & Physical Properties
| Molecular Formula | C94H128N22O31S2 |
|---|---|
| Molecular Weight | 2126.28000 |
| Exact Mass | 2124.86000 |
| PSA | 892.53000 |
| LogP | 2.22240 |
| InChIKey | FUTWNIPXZKAJHO-WQVXRQFFSA-N |
| SMILES | CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCNC(=N)N)NC(=O)C1CCC(=O)N1)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccccc1)C(N)=O |
| Storage condition | −20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles7
More Articles| Processing of the gastrin precursor. Modulation of phosphorylated, sulfated, and amidated products. J. Biol. Chem. 265(35) , 21476-81, (1990) Post-translational processing of the precursor for rat gastrin yields products that include peptides phosphorylated at Ser96, amidated at Phe92, and sulfated at Tyr87 or Tyr103. The phosphorylation si... | |
| Gastrin-producing endocrine cells: a novel source of histamine in the rat stomach. Endocrinology 139(10) , 4404-15, (1998) Gastrin and histamine both potently stimulate secretion of acid into the gastric lumen. How these agents interact and how their release is controlled is poorly understood. Therefore, we decided to loo... | |
| Histidine decarboxylase expression and histamine metabolism in gastric oxyntic mucosa during hypergastrinemia and carcinoid tumor formation. Endocrinology 137(10) , 4435-42, (1996) Histamine is an important stimulator of gastric acid secretion. In experimental animals, inhibition of acid secretion by long term histamine2 receptor blockade causes hypergastrinemia, proliferation o... |
Synonyms
| gastrin i (rat) |
| gastrin (1-17),rat |
| pyr-rppmeeeeeaygwmdf-nh2 |
| gastrin-1,rat |
| gastrin (rat) |
| pglu-arg-pro-pro-met-glu-glu-glu-glu-glu-ala-tyr-gly-trp-met-asp-phe-nh2 |
| gastrin,rat (1-17) |
| gastrin i |
