CAS 494-90-6|UNII:LK024V9U3C
| Common Name | UNII:LK024V9U3C | ||
|---|---|---|---|
| CAS Number | 494-90-6 | Molecular Weight | 150.218 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 210.7±9.0 °C at 760 mmHg |
| Molecular Formula | C10H14O | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 75.6±0.0 °C |
Names
| Name | menthofuran |
|---|---|
| Synonym | More Synonyms |
UNII:LK024V9U3C BiologicalActivity
| Description | Menthofuran is a proximate toxic metabolite of (R)-(+)-Pulegone. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| References | [1]. Gordon WP, et al. The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran. Drug Metab Dispos. 1987 Sep-Oct;15(5):589-94. [2]. Mahmoud SS, et al. Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14481-6. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 210.7±9.0 °C at 760 mmHg |
| Molecular Formula | C10H14O |
| Molecular Weight | 150.218 |
| Flash Point | 75.6±0.0 °C |
| Exact Mass | 150.104462 |
| PSA | 13.14000 |
| LogP | 4.02 |
| Vapour Pressure | 0.3±0.4 mmHg at 25°C |
| Index of Refraction | 1.490 |
| InChIKey | YGWKXXYGDYYFJU-UHFFFAOYSA-N |
| SMILES | Cc1coc2c1CCC(C)C2 |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | DF7995750 |
Articles26
More Articles| Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr. Drug Metab. 6 , 413-54, (2005) The inhibition of human cytochrome P450s (CYPs) is one of the most common mechanisms which can lead to drug-drug interactions. The inhibition of CYPs can be reversible (competitive or non-competitive)... | |
| In vitro production of M. × piperita not containing pulegone and menthofuran. Acta Biochim. Pol. 59(3) , 417-23, (2012) The essential oils (EOs) and static headspaces (HSs) of in vitro plantlets and callus of Mentha x piperita were characterized by GC-MS analysis. Leaves were used as explants to induce in vitro plant m... | |
| Volatile organic compounds from rhizobacteria increase biosynthesis of essential oils and growth parameters in peppermint (Mentha piperita). Plant Physiol. Biochem. 49(10) , 1177-82, (2011) Volatile organic compounds (VOCs), characterized by low molecular weight and high vapor pressure, are produced by all organisms as part of normal metabolism, and play important roles in communication ... |
Synonyms
| 3,9-Epoxy-p-mentha-3,8-diene |
| 3,6-dimethyl-4,5,6,7-tetrahydrobenzo[b]furan |
| MENTHOFURAN(SG) |
| FEMA 3235 |
| EINECS 207-795-5 |
| Menthofurane |
| 4,5,6,7-Tetrahydro-3,6-dimethyl-1-benzofuran |
| MENTHOFURAN |
| UNII:LK024V9U3C |
| Menthofuran 10GR |
| 3,6-dimethyl-4,5,6,7-tetrahydro-benzofuran |
| Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl- |
| p-Mentha-3,8-diene,3,9-epoxy |
| MENTHOFURAN,NATURAL |
| MENTHOFURAN WITH GC |
| MFCD00041851 |
| 3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran |
| 2-4,5,6,7-tetrahydro-3,6-dimethylbenzofuran |
