CAS 581-31-7|Suberosin

Introduction：Basic information about CAS 581-31-7|Suberosin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Suberosin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Suberosin
CAS Number	581-31-7	Molecular Weight	244.286
Density	1.1±0.1 g/cm3	Boiling Point	393.3±42.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₆O₃	Melting Point	/
MSDS	/	Flash Point	166.0±22.5 °C

Names

Name	7-methoxy-6-(3-methylbut-2-enyl)chromen-2-one
Synonym	More Synonyms

Suberosin BiologicalActivity

Description	Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB[1][2].
Related Catalog	Research Areas >>Inflammation/Immunology
References	[1]. Y-C Chen, et al. Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NF-jB. British Journal of Pharmacology (2007) 150, 298-312. [2]. Golfakhrabadi F, et al. Anticoagulant activity of isolated coumarins (suberosin and suberenol) and toxicity evaluation of Ferulago carduchorum in rats. Pharm Biol. 2014 Oct;52(10):1335-40.

Description

Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation of the transcription factors NF-AT and NF-κB[1][2].

Related Catalog

Research Areas >>Inflammation/Immunology

References

[1]. Y-C Chen, et al. Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NF-jB. British Journal of Pharmacology (2007) 150, 298-312.

[2]. Golfakhrabadi F, et al. Anticoagulant activity of isolated coumarins (suberosin and suberenol) and toxicity evaluation of Ferulago carduchorum in rats. Pharm Biol. 2014 Oct;52(10):1335-40.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	393.3±42.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₆O₃
Molecular Weight	244.286
Flash Point	166.0±22.5 °C
Exact Mass	244.109940
PSA	39.44000
LogP	3.87
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.557
InChIKey	RSZDAYHEZSRVHS-UHFFFAOYSA-N
SMILES	COc1cc2oc(=O)ccc2cc1CC=C(C)C

Safety Information

Hazard Codes	Xi

Synonyms

2H-1-Benzopyran-2-one, 7-methoxy-6- (3-methyl-2-butenyl)-

SUBEROSIN

7-Methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one

7-Methoxy-6-(3-methyl-2-buten-1-yl)-2H-chromen-2-one

2H-1-Benzopyran-2-one, 7-methoxy-6-(3-methyl-2-buten-1-yl)-

2H-1-Benzopyran-2-one, 7-methoxy-6-(3-methyl-2-butenyl)-

Coumarin, 7-methoxy-6- (3-methyl-2-butenyl)-

7-methoxy-6-prenylcoumarin

Coumarin, 7-methoxy-6-(3-methyl-2-butenyl)-

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