CAS 22264-50-2|1-Aminocyclobutanecarboxylic acid
Introduction：Basic information about CAS 22264-50-2|1-Aminocyclobutanecarboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1-Aminocyclobutanecarboxylic acid | ||
|---|---|---|---|
| CAS Number | 22264-50-2 | Molecular Weight | 115.131 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 241.1±23.0 °C at 760 mmHg |
| Molecular Formula | C5H9NO2 | Melting Point | 261ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 99.6±22.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1-Aminocyclobutanecarboxylic acid |
|---|---|
| Synonym | More Synonyms |
1-Aminocyclobutanecarboxylic acid BiologicalActivity
| Description | 1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
| References | [1]. Atsushi Inanobe, et al. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 241.1±23.0 °C at 760 mmHg |
| Melting Point | 261ºC (dec.) |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.131 |
| Flash Point | 99.6±22.6 °C |
| Exact Mass | 115.063332 |
| PSA | 63.32000 |
| LogP | -0.62 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.540 |
| Storage condition | Store at RT |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | GU1336000 |
| HS Code | 2922499990 |
Preparation
Customs
| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
Articles19
More Articles| [Change in the level of 1-aminochloropropane-1-carbonic acid. Activity of a protein inhibitor of polygalacturonase, intensity of formation of oligouronides in apples during ripening and treatment with haloethane derivatives and aminoethoxyvinylglycine]. Prikl. Biokhim. Mikrobiol. 39(4) , 461-4, (2003) We studied changes in the intensity of ethylene release and accumulation of 1-aminocyclopropane-1-carboxylic acid during ripening of two apple varieties characterized by various physiological states a... | |
| Glycine antagonist action of 1-aminocyclobutane-1-carboxylate (ACBC) in Xenopus oocytes injected with rat brain mRNA. Eur. J. Pharmacol. 167(2) , 291-4, (1989) ACBC has been reported to have the binding profile of an antagonist at the glycine site of the NMDA receptor. In Xenopus oocytes injected with rat brain mRNA, we have confirmed the antagonist action o... | |
| Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme. Chem. Biol. 5(1) , 49-57, (1998) The chemical mechanism of the final step of ethylene biosynthesis (the conversion of 1-aminocyclopropanecarboxylic acid, ACC, to ethylene by ACC oxidase, the ethylene-forming enzyme, EFE) is poorly un... |
Synonyms
| N-Methylquipazine dimaleate |
| 1-amino-cyclobutanecarboxylicaci |
| ACBC-OH |
| MFCD00661068 |
| cb1700 |
| AC4C-OH |
| Cyclobutanecarboxylic acid, 1-amino- |
| 1-Aminocyclobutaneca |
| 1-Amino-1-carboxycyclobutane |
| 1-Amino-1-cyclobutanecarboxylic acid |
| 1-aminocyclobutane-1-carboxylic acid |
| 1,1-ACCB |
| 1-Aminocyclobutanecarboxylic acid |
| 1-Aminocyclobutan-1-carboxylic acid |
| aminocyclobutane carboxylic acid |
| ACBC |
