Introduction：Basic information about CAS 3420-72-2|Flavokawain A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Flavokawain A |
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| CAS Number | 3420-72-2 | Molecular Weight | 314.332 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 529.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C18H18O5 | Melting Point | 112-116 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 193.2±23.6 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 2'-hydroxy-4,4',6'-trimethoxychalcone |
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| Synonym | More Synonyms |
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Flavokawain A BiologicalActivity
| Description | Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| References | [1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 529.9±50.0 °C at 760 mmHg |
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| Melting Point | 112-116 °C(lit.) |
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| Molecular Formula | C18H18O5 |
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| Molecular Weight | 314.332 |
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| Flash Point | 193.2±23.6 °C |
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| Exact Mass | 314.115417 |
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| PSA | 64.99000 |
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| LogP | 3.96 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.600 |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2914509090 |
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Customs
| HS Code | 2914509090 |
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| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| FLAVOKAWIN A |
| 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one |
| Flavokavin A |
| MFCD00017174 |
| 2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone |
| 2'-Hydroxy-4,4',6'-trimethoxy |
| flavokawain-A |
| 2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone |
| 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)- |
| 2'-hydroxy-4,4',6'-trimethoxy-chalcone |
| Flavokawain A |
