CAS 3348-03-6|6-Carboxyfluorescein Diacetate
| Common Name | 6-Carboxyfluorescein Diacetate | ||
|---|---|---|---|
| CAS Number | 3348-03-6 | Molecular Weight | 460.389 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 701.6±60.0 °C at 760 mmHg |
| Molecular Formula | C25H16O9 | Melting Point | 152–153°C |
| MSDS | ChineseUSA | Flash Point | 245.1±26.4 °C |
Names
| Name | 6-carboxyfluorescein diacetate |
|---|---|
| Synonym | More Synonyms |
6-Carboxyfluorescein Diacetate BiologicalActivity
| Description | 6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>OthersDye Reagents |
| References | [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Graber ML, et al. Characteristics of fluoroprobes for measuring intracellular pH. Anal Biochem. 1986 Jul;156(1):202-12. [3]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 701.6±60.0 °C at 760 mmHg |
| Melting Point | 152–153°C |
| Molecular Formula | C25H16O9 |
| Molecular Weight | 460.389 |
| Flash Point | 245.1±26.4 °C |
| Exact Mass | 460.079437 |
| PSA | 125.43000 |
| LogP | 2.45 |
| Appearance of Characters | Light yellow or off-white solid |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.702 |
| InChIKey | QMOGCCYGOPYYNT-UHFFFAOYSA-N |
| SMILES | CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccc(C(=O)O)cc21 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: soluble |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932999099 |
Customs
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6-FAM DA |
| 6-CFDA 6-Carboxy-di-O-acetylfluorescein |
| 6-CFDA |
| MFCD00036871 |
| 6-Carboxyfluorescein diacetate |
| 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid |
| 6-Carboxy-di-O-acetylfluorescein,6-CFDA |
| 5,6-diacetyl FAM-SE |
| 6-CARBOXY-DI-O-ACETYLFLUORESCEIN |
| Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo- |
| 3',6'-Diacetoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid |
| 6-FAM DIACETATE |
| 6-Carboxyfluorescein diacetate,6-CFDA,6-Carboxy-di-O-acetylfluorescein |
| 6-CARBOXYFLUORESCEINE DIACETATE |
