Introduction：Basic information about CAS 34218-84-3|2'-O-Methyl-5-Iodo-Uridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-O-Methyl-5-Iodo-Uridine |
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| CAS Number | 34218-84-3 | Molecular Weight | 384.12 |
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| Density | 2.04±0.1 g/cm3(Predicted) | Boiling Point | / |
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| Molecular Formula | C10H13IN2O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2'-(o-methyl)-5-iodouridine |
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| Synonym | More Synonyms |
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2'-O-Methyl-5-Iodo-Uridine BiologicalActivity
| Description | 2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.04±0.1 g/cm3(Predicted) |
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| Molecular Formula | C10H13IN2O6 |
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| Molecular Weight | 384.12 |
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| Exact Mass | 383.98200 |
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| PSA | 113.78000 |
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| InChIKey | PLVDDNNLEWFJNQ-JXOAFFINSA-N |
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| SMILES | COC1C(O)C(CO)OC1n1cc(I)c(=O)[nH]c1=O |
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| Storage condition | 2-8℃ |
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Synonyms
| 2'-OMe-5-I-Uridine |
| 5-Iodo-2'-O-methyluridin |
| 5-IODO-2'-O-METHYLURIDINE |
| 2'-OMe-5-I-U |
| Uridine,5-iodo-2'-O-Methyl |
| 2'-O-Methyl-5-Iodo-Uridine |
