CAS 451-69-4|3-(2-Fluorophenyl)acrylic acid

Introduction：Basic information about CAS 451-69-4|3-(2-Fluorophenyl)acrylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	3-(2-Fluorophenyl)acrylic acid
CAS Number	451-69-4	Molecular Weight	166.149
Density	1.3±0.1 g/cm3	Boiling Point	281.6±15.0 °C at 760 mmHg
Molecular Formula	C₉H₇FO₂	Melting Point	178-180 °C(lit.)
MSDS	ChineseUSA	Flash Point	124.1±20.4 °C

Names

Name	2-Fluorocinnamic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	281.6±15.0 °C at 760 mmHg
Melting Point	178-180 °C(lit.)
Molecular Formula	C₉H₇FO₂
Molecular Weight	166.149
Flash Point	124.1±20.4 °C
Exact Mass	166.043015
PSA	37.30000
LogP	2.47
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.591

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD9081000

CHEMICAL NAME :: Cinnamic acid, o-fluoro-

CAS REGISTRY NUMBER :: 451-69-4

BEILSTEIN REFERENCE NO. :: 1863963

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H7-F-O2

MOLECULAR WEIGHT :: 166.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,285,1953

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GD9081000
HS Code	2916399090

Customs

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles1

(S,E)-N-[1-(3-heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity.

Bioorg. Med. Chem. Lett. 15(2) , 363-6, (2005)

Replacement of the morpholinyl moiety in (S,E)-N-[1-(3-morpholinophenyl)ethyl]-3-phenylacrylamide (1) with heteroaryl groups led to the identification of (S,E)-N-1-[3-(6-fluoropyridin-3-yl)phenyl]ethy...

Synonyms

3-(2-fluorophenyl)-2-propenoic acid

2-Propenoic acid, 3-(2-fluorophenyl)-, (2E)-

3-(2-Fluorophenyl)acrylic acid

(2E)-3-(2-Fluorophenyl)acrylic acid

2-fluoro-cinnamic acid

(2E)-3-(2-fluorophenyl)prop-2-enoic acid

3-(2-fluoro-phenyl)acrylic acid

TRANS-2-FLUOROCINNAMIC ACID

2-Fluor-zimtsaeure

MFCD00004370

EINECS 207-195-3

2-Fluorocinnamic acid

RARECHEM BK HC T305

o-fluoro-cinnamicaci

2-Fluorociamic acid

Cinnamic acid,o-fluoro

2-fluorincinnamic acid

O-FLUOROCINNAMIC ACID

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