Introduction：Basic information about CAS 77544-60-6|Tetraethylene glycol monotosylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetraethylene glycol monotosylate |
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| CAS Number | 77544-60-6 | Molecular Weight | 348.41200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C15H24O7S | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | >230 °F |
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| Symbol |
GHS05, GHS06 | Signal Word | Danger |
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Names
| Name | 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol |
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| Synonym | More Synonyms |
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Tetraethylene glycol monotosylate BiologicalActivity
| Description | Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16(7):763-72. |
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Chemical & Physical Properties
| Molecular Formula | C15H24O7S |
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| Molecular Weight | 348.41200 |
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| Exact Mass | 348.12400 |
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| PSA | 110.67000 |
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| LogP | 1.21000 |
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| InChIKey | FGDJUEZBMFELRW-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(S(=O)(=O)OCCOCCOCCOCCO)cc1 |
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Safety Information
| Symbol |
GHS05, GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301-H314 |
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| Precautionary Statements | P280-P301 + P310-P305 + P351 + P338-P310 |
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| RIDADR | UN 2927 8(6.1) / PGII |
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| HS Code | 2909499000 |
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| Flash Point(F) | >230 °F |
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| Flash Point(C) | >110 °C |
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Customs
| HS Code | 2909499000 |
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| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| toluene-4-sulfonic acid 2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester |
| tetraglycol-Ts |
| Ethanol,2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,1-(4-Methylbenzenesulfonate) |
| [2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethyl-4-methylbenzenesulfonate |
| Ts-tetraglycol |
| tetraethyleneglycol monotosylate |
