Introduction：Basic information about CAS 181630-15-9|Picoplatin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Picoplatin |
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| CAS Number | 181630-15-9 | Molecular Weight | 376.147 |
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| Density | / | Boiling Point | 127.5ºC at 760mmHg |
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| Molecular Formula | C6H7Cl2NPt | Melting Point | / |
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| MSDS | / | Flash Point | 26.1ºC |
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Names
| Name | azane,2-methylpyridine,platinum(2+),dichloride |
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| Synonym | More Synonyms |
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Picoplatin BiologicalActivity
| Description | Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. J Holford, et al. In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473. Br J Cancer. 1998;77(3):366-73. |
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Chemical & Physical Properties
| Boiling Point | 127.5ºC at 760mmHg |
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| Molecular Formula | C6H7Cl2NPt |
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| Molecular Weight | 376.147 |
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| Flash Point | 26.1ºC |
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| Exact Mass | 374.986908 |
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| PSA | 12.89000 |
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| LogP | 2.76650 |
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| Vapour Pressure | 13.5mmHg at 25°C |
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Safety Information
| RIDADR | UN 2811 |
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| Packaging Group | II |
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| Hazard Class | 6.1(a) |
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Synonyms
| Platinum(2+) chloride - 2-methylpyridine ammoniate (1:2:1:1) |
| Picoplatin |
| cis-amminedichloro(2-methylpyridine)platinum(II) |
| cis-amminedichlorido(2-methylpyridine)platinum(II) |
| cis-amminedichloro(2-picoline)platinum(II) |
| Pyridine, 2-methyl-, platinum(2+) salt, hydrochloride, ammoniate (1:1:2:1) |
| ZD 0473 |
| Picoplatin [INN:BAN] |
| (SP-4-3)-Amminedichloro(2-methylpyridine)platinium |
| AMD 473 |
| cis-PtCl2(NH3)(2-picoline) |
