Introduction：Basic information about CAS 77-22-5|caramiphen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | caramiphen |
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| CAS Number | 77-22-5 | Molecular Weight | 289.41200 |
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| Density | 1.038g/cm3 | Boiling Point | 392.1ºC at 760 mmHg |
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| Molecular Formula | C18H27NO2 | Melting Point | / |
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| MSDS | / | Flash Point | 124.8ºC |
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Names
| Name | 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.038g/cm3 |
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| Boiling Point | 392.1ºC at 760 mmHg |
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| Molecular Formula | C18H27NO2 |
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| Molecular Weight | 289.41200 |
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| Flash Point | 124.8ºC |
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| Exact Mass | 289.20400 |
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| PSA | 29.54000 |
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| LogP | 3.38340 |
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| Index of Refraction | 1.523 |
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| InChIKey | OFAIGZWCDGNZGT-UHFFFAOYSA-N |
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| SMILES | CCN(CC)CCOC(=O)C1(c2ccccc2)CCCC1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- GY3700000
- CHEMICAL NAME :
- Cyclopentanecarboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 77-22-5
- BEILSTEIN REFERENCE NO. :
- 2144901
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H27-N-O2
- MOLECULAR WEIGHT :
- 289.46
- WISWESSER LINE NOTATION :
- L5TJ AVO2N2&2 AR
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APPNAH Acta Physiologica et Pharmacologica Neerlandica. (Amsterdam, Netherlands) V.1-15, 1950-69. For publisher information, see EJPHAZ. Volume(issue)/page/year: 1,4,1950
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,293,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 365 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HPPAAL Helvetica Physiologia et Pharmacologica Acta. (Basel, Switzerland) V.1-26, 1943-68. Discontinued. Volume(issue)/page/year: 16,277,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 570 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HPPAAL Helvetica Physiologia et Pharmacologica Acta. (Basel, Switzerland) V.1-26, 1943-68. Discontinued. Volume(issue)/page/year: 16,277,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 67 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 76,1282,1946
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Synonyms
| Caramiphene [INN-French] |
| CYCLOPENTANECARBOXYLIC ACID,1-PHENYL-,2-(DIETHYLAMINO)ETHYL ESTER |
| Caramiphenum [INN-Latin] |
| Pentaphen (pharmaceutical) |
| 1-Phenyl-cyclopentan-1-carbonsaeure-<2-diethylamino-ethylester> |
| 1-Phenyl-cyclopentan-carbonsaeure-(1)-<2-diethylamino-ethylester> |
| Parpanil |
| Caramiphen |
| EINECS 201-013-6 |
| Caramifenio [INN-Spanish] |
| 1-phenyl-cyclopentanecarboxylic acid-(2-diethylamino-ethyl ester) |
| 1-Phenyl-cyclopentancarbonsaeure-(2-diaethylamino-aethylester) |
| 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate |
