Introduction:Basic information about CAS 637-84-3|H-Gly-Gly-Gly-Gly-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Tetraglycine is a oligopeptide composed of four glycine monomers[1].
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In Vivo
Tetraglycine and Triglycine (1.0 μmol glycine/g body wt, injected into a central vein) results in greater glycine concentration in the kidney than injection of either Glycine (HY-Y0966) or Diglycine[1]. Animal Model: Male Sprague-Dawley rats (270-300 g)[1] Dosage: 1.0 μmol glycine/g body wt Administration: IV, injected over a period of 30 s Result: Five minutes after the Tetraglycine injection, there were accumulations of diglvcine, triglvcine, and Tetraglycine in the kidney.
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Tetrapeptides derived from glycine and beta-alanine were hooked at the C-3beta position of the modified cholic acid to realize novel linear tetrapeptide-linked cholic acid derivatives. All the synthes...
Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.
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The human intestinal oligopeptide transporter (PEPT1) facilitates the absorption of dipeptides, tripeptides, and many peptidomimetic drugs. In this study, a large number of peptides were selected to i...