CAS 498-24-8|Mesaconic acid
Introduction：Basic information about CAS 498-24-8|Mesaconic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mesaconic acid | ||
|---|---|---|---|
| CAS Number | 498-24-8 | Molecular Weight | 130.09900 |
| Density | 1.387 g/cm3 | Boiling Point | 336.6ºC at 760 mmHg |
| Molecular Formula | C5H6O4 | Melting Point | 200-202ºC |
| MSDS | ChineseUSA | Flash Point | 171.5ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | mesaconic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.387 g/cm3 |
|---|---|
| Boiling Point | 336.6ºC at 760 mmHg |
| Melting Point | 200-202ºC |
| Molecular Formula | C5H6O4 |
| Molecular Weight | 130.09900 |
| Flash Point | 171.5ºC |
| Exact Mass | 130.02700 |
| PSA | 74.60000 |
| LogP | 0.10190 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.514 |
| InChIKey | HNEGQIOMVPPMNR-NSCUHMNNSA-N |
| SMILES | CC(=CC(=O)O)C(=O)O |
| Storage condition | 2-8°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,147,1954
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | OX5075000 |
| HS Code | 2917190090 |
Customs
| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles27
More Articles| The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes. J. Pharmacol. Exp. Ther. 352(1) , 90-7, (2015) Monomethylfumarate (MMF) is thought to be the bioactive ingredient of the drug Fumaderm (Biogen Idec, Cambridge, MA), licensed in Germany since 1994 for the treatment of moderate-to-severe psoriasis. ... | |
| In vitro pharmacokinetics of anti-psoriatic fumaric acid esters. BMC Pharmacol. 4 , 22, (2004) Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist o... | |
| The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. Biochem. Biophys. Res. Commun. 375(4) , 562-5, (2008) Nicotinic acid has been used for several decades to treat dyslipidemia. In mice, the lipid-lowing effect of nicotinic acid is mediated by the Gi coupled receptor PUMA-G. In humans, high (GPR109A) and ... |
Synonyms
| Methylfumaric Acid |
| EINECS 207-859-2 |
| Mesaconic Acid |
| MFCD00002653 |
| 2-Butenedioic acid,2-methyl-, (2E)- |
