CAS 501-98-4|trans-4-Hydroxycinnamic acid
Introduction：Basic information about CAS 501-98-4|trans-4-Hydroxycinnamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | trans-4-Hydroxycinnamic acid | ||
|---|---|---|---|
| CAS Number | 501-98-4 | Molecular Weight | 164.158 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 346.1±17.0 °C at 760 mmHg |
| Molecular Formula | C9H8O3 | Melting Point | 214ºC |
| MSDS | ChineseUSA | Flash Point | 177.3±17.4 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | p-Coumaric acid |
|---|---|
| Synonym | More Synonyms |
trans-4-Hydroxycinnamic acid BiologicalActivity
| Description | p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>CancerNatural Products >>Phenylpropanoids |
| References | [1]. Jaganathan SK, et al. Events associated with apoptotic effect of p-Coumaric acid in HCT-15 colon cancer cells. World J Gastroenterol. 2013 Nov 21;19(43):7726-34. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 346.1±17.0 °C at 760 mmHg |
| Melting Point | 214ºC |
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.158 |
| Flash Point | 177.3±17.4 °C |
| Exact Mass | 164.047348 |
| PSA | 57.53000 |
| LogP | 1.88 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.660 |
| InChIKey | NGSWKAQJJWESNS-ZZXKWVIFSA-N |
| SMILES | O=C(O)C=Cc1ccc(O)cc1 |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2850 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?). Volume(issue)/page/year: 3,675,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1160 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?). Volume(issue)/page/year: 3,675,1969
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | GD9095000 |
| HS Code | 2918290000 |
Customs
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
Articles152
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Synonyms
| 4-Hydroxy cinnamic acid |
| (2E)-3-(4-Hydroxyphenyl)acrylic acid |
| trans-p-Cumaric Acid |
| EINECS 231-000-0 |
| 3-(4-Hydroxy-phenyl)-acrylic acid |
| trans-p-Coumaric Acid |
| 2-propenoic acid, 3-(4-hydroxyphenyl)- |
| E-4-Hydroxycinnamic Acid |
| (E)-3-(4-Hydroxyphenyl)acrylic acid |
| 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (2E)- |
| 4-Coumaric acid |
| trans-4-Hydroxycinnamic Acid |
| p-Hydroxycinnamic acid,predominantly trans |
| MFCD00004399 |
| 4-Hydroxycinnamic acid |
