CAS 943-89-5|(E)-3-(4-Methoxyphenyl)acrylic acid
| Common Name | (E)-3-(4-Methoxyphenyl)acrylic acid | ||
|---|---|---|---|
| CAS Number | 943-89-5 | Molecular Weight | 178.185 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 342.6±17.0 °C at 760 mmHg |
| Molecular Formula | C10H10O3 | Melting Point | 173.5ºC |
| MSDS | ChineseUSA | Flash Point | 138.6±14.4 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | (E)-4-Methoxycinnamic Acid |
|---|---|
| Synonym | More Synonyms |
(E)-3-(4-Methoxyphenyl)acrylic acid BiologicalActivity
| Description | (E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic DiseaseResearch Areas >>Neurological Disease |
| References | [1]. Sirichan Tachai, et al. Uncommon secondary metabolites from Etlingera pavieana rhizomes. Nat Prod Res. 2016 Oct;30(19):2215-9. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 342.6±17.0 °C at 760 mmHg |
| Melting Point | 173.5ºC |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.185 |
| Flash Point | 138.6±14.4 °C |
| Exact Mass | 178.062988 |
| PSA | 46.53000 |
| LogP | 2.36 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.591 |
| InChIKey | AFDXODALSZRGIH-QPJJXVBHSA-N |
| SMILES | COc1ccc(C=CC(=O)O)cc1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | UD3391300 |
| HS Code | 2916399090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles21
More Articles| Antimicrobial activity of natural products from the flora of Northern Ontario, Canada. Pharm. Biol. 53(6) , 800-6, (2015) The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only ... | |
| A practical procedure for the large-scale preparation of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate, a key intermediate for diltiazem. J. Org. Chem. 67(13) , 4599-601, (2002) A practical synthesis of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate (-)-2, a key intermediate for diltiazem (1), was developed. Treatment of methyl (E)-4-methoxycinnamate 3 with chiral dioxirane, gen... | |
| Enzymatic synthesis of cinnamic acid derivatives. Biotechnol. Lett. 28(8) , 581-5, (2006) Using Novozym 435 as catalyst, the syntheses of ethyl ferulate (EF) from ferulic acid (4-hydroxy 3-methoxy cinnamic acid) and ethanol, and octyl methoxycinnamate (OMC) from p-methoxycinnamic acid and ... |
Synonyms
| 3-(4-Methoxy-phenyl)-acrylic acid |
| trans-4-Methoxycinnamic acid |
| 4-MeOC6H4CH=CHCOOH |
| 4-methoxycinnamate |
| RARECHEM BK HC T257 |
| 2-Propenoic acid, 3-(4-methoxyphenyl)-, (2E)- |
| 2-Propenoic acid, 3- (4-methoxyphenyl)- |
| (E)-3-(4-methoxyphenyl)acrylic acid |
| 4-Methoxy-(2E)-cinnamic acid |
| 4-Methoxyciamic acid |
| p-coumaric acid methyl ether |
| (2E)-3-(4-methoxyphenyl)prop-2-enoic acid |
| UNII-6G4ML8401A |
| (E)-p-methoxycinnamic acid |
| 4-Methoxycinnamic acid |
| (2E)-3-(4-Methoxyphenyl)acrylic acid |
| 4-methoxy-(E)-cinnamic acid |
| EINECS 213-405-4 |
| (E)-3-(4-Methoxyphenyl)acrylate |
| para-methoxycinnamic acid |
| PMCA |
| MFCD00004398 |
| (2E)-3-(4-Methoxyphenyl)-2-propenoic acid |
| para-methoxycinnamate |
