CAS 4928-02-3|7-aminonitrazepam
Introduction：Basic information about CAS 4928-02-3|7-aminonitrazepam, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-aminonitrazepam | ||
|---|---|---|---|
| CAS Number | 4928-02-3 | Molecular Weight | 251.28300 |
| Density | 1.3g/cm3 | Boiling Point | 495.8ºC at 760 mmHg |
| Molecular Formula | C15H13N3O | Melting Point | 242-244ºC |
| MSDS | / | Flash Point | 253.6ºC |
| Symbol | GHS02, GHS07 | Signal Word | Danger |
Names
| Name | 7-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.3g/cm3 |
|---|---|
| Boiling Point | 495.8ºC at 760 mmHg |
| Melting Point | 242-244ºC |
| Molecular Formula | C15H13N3O |
| Molecular Weight | 251.28300 |
| Flash Point | 253.6ºC |
| Exact Mass | 251.10600 |
| PSA | 67.48000 |
| LogP | 2.21310 |
| Index of Refraction | 1.683 |
| InChIKey | OYOUQHVDCKOOAL-UHFFFAOYSA-N |
| SMILES | Nc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 44,209,1991
Safety Information
| Symbol | GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H302 + H332-H319 |
| Precautionary Statements | P210-P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Phrases | 11-20/21/22-36 |
| Safety Phrases | 16-36/37 |
| RIDADR | UN 1648 3 / PGII |
Articles10
More Articles| Measurement of benzodiazepines in urine by liquid chromatography-tandem mass spectrometry: confirmation of samples screened by immunoassay. Ann. Clin. Biochem. 47(Pt 2) , 111-7, (2010) Liquid chromatography linked to tandem mass spectrometry (LC/MS/MS) provides the ability to identify a range of benzodiazepines in accordance with European Union criteria and is an attractive method f... | |
| A highly sensitive method for the determination of 7-aminonitrazepam, a metabolite of nitrazepam, in human urine using high-performance electrospray liquid chromatography tandem mass spectrometry. Biomed. Chromatogr. 23(7) , 740-4, (2009) A highly sensitive method has been developed for the determination of urinary 7-aminonitrazepam (7-ANZP), the major metabolite of nitrazepam, using high-performance electrospray liquid chromatography ... | |
| Determination of nitrazepam and its main metabolites in urine by thin-layer chromatography and direct densitometry. J. Chromatogr. A. 339(1) , 163-9, (1985) A method for the direct quantitative densitometry of nitrazepam and its main metabolites (7-aminonitrazepam, 7-acetamidonitrazepam and 2-amino-5-nitrobenzophenone) in urine was developed. The unchange... |
Synonyms
| 7-Amino-1,2-dihydro-3H-1,4-benzodiazepin-2-one |
| 7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin |
| 7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one |
| 7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-benzo<e>-1,4-diazepin |
| 7-amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one |
| 7-Amino Nitrazepam |
| Ro 5-3072 |
| 7-Amino-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one |
| 2H-1,4-Benzodiazepin-2-one,7-amino-1,3-dihydro-5-phenyl |
| 7-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one |
| 7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepinon-(2) |
| 7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
