CAS 33996-58-6|Etiracetam
| Common Name | Etiracetam | ||
|---|---|---|---|
| CAS Number | 33996-58-6 | Molecular Weight | 170.209 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 395.9±25.0 °C at 760 mmHg |
| Molecular Formula | C8H14N2O2 | Melting Point | / |
| MSDS | / | Flash Point | 193.2±23.2 °C |
| Symbol | GHS07, GHS09 | Signal Word | Warning |
Names
| Name | 2-(2-oxopyrrolidin-1-yl)butanamide |
|---|---|
| Synonym | More Synonyms |
Etiracetam BiologicalActivity
| Description | Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059)[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Neurological Disease |
| Target | Acetylcholine[1]. |
| References | [1]. Hovinga CA, et al. Levetiracetam: a novel antiepileptic drug. Pharmacotherapy. 2001 Nov;21(11):1375-88. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 395.9±25.0 °C at 760 mmHg |
| Molecular Formula | C8H14N2O2 |
| Molecular Weight | 170.209 |
| Flash Point | 193.2±23.2 °C |
| Exact Mass | 170.105530 |
| PSA | 64.39000 |
| LogP | -0.67 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.519 |
| InChIKey | HPHUVLMMVZITSG-UHFFFAOYSA-N |
| SMILES | CCC(C(N)=O)N1CCCC1=O |
| Storage condition | 2-8℃ |
Safety Information
| Symbol | GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319-H411 |
| Precautionary Statements | P273-P305 + P351 + P338 |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36 |
| Safety Phrases | S26 |
| RIDADR | UN 3077 9 / PGIII |
Articles27
More Articles| Inhibition of excitatory synaptic transmission in hippocampal neurons by levetiracetam involves Zn²⁺-dependent GABA type A receptor-mediated presynaptic modulation. J. Pharmacol. Exp. Ther. 348(2) , 246-59, (2014) Levetiracetam (LEV) is an antiepileptic drug with a unique but as yet not fully resolved mechanism of action. Therefore, by use of a simplified rat-isolated nerve-bouton preparation, we have investiga... | |
| Efficacy and safety of pregabalin versus levetiracetam as adjunctive therapy in patients with partial seizures: a randomized, double-blind, noninferiority trial. Epilepsia 55(7) , 1048-57, (2014) To assess the comparative efficacy and safety of pregabalin and levetiracetam for the reduction of seizure frequency in patients with partial seizures.This was a randomized, double-blind, flexible-dos... | |
| The established status epilepticus trial 2013. Epilepsia 54 Suppl 6 , 89-92, (2013) Benzodiazepine-refractory status epilepticus (established status epilepticus, ESE) is a relatively common emergency condition with several widely used treatments. There are no controlled, randomized, ... |
Synonyms
| 1-Pyrrolidineacetamide, α-ethyl-2-oxo- |
| UCB 6474 |
| (±)-a-Ethyl-2-oxo-1-pyrrolidineacetamide |
| ucb L059 |
| T5NVTJ AY2&VZ |
| Etiracetam |
| 2-(2-Oxo-1-pyrrolidinyl)butanamide |
| α-Ethyl-2-oxo-1-pyrrolidineacetamide |
| UNII:230447L0GL |
| Levetiracetam Racemic Mixture |
| 乙拉西坦 |
| 2-(2-Oxopyrrolidin-1-yl)butyramide |
| (±)-α-Ethyl-2-oxo-1-pyrrolidineacetamide |
| 2-(2-oxopyrrolidin-1-yl)butanamide |
