Introduction:Basic information about CAS 76474-56-1|Dihydrocurcumin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dihydrocurcumin |
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| CAS Number | 76474-56-1 | Molecular Weight | 370.39600 |
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| Density | 1.277g/cm3 | Boiling Point | 616.3ºC at 760 mmHg |
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| Molecular Formula | C21H22O6 | Melting Point | / |
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| MSDS | / | Flash Point | 217.8ºC |
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Names
| Name | (4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-4,6-heptadie n-3-one |
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Dihydrocurcumin BiologicalActivity
| Description | Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Yu Q, et al. Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. Biomed Pharmacother. 2018 Jul;103:1327-1336. |
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Chemical & Physical Properties
| Density | 1.277g/cm3 |
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| Boiling Point | 616.3ºC at 760 mmHg |
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| Molecular Formula | C21H22O6 |
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| Molecular Weight | 370.39600 |
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| Flash Point | 217.8ºC |
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| Exact Mass | 370.14200 |
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| PSA | 96.22000 |
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| LogP | 3.77200 |
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| Index of Refraction | 1.634 |
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| Storage condition | 2-8℃ |
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