Introduction：Basic information about CAS 107429-63-0|Lintopride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Lintopride |
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| CAS Number | 107429-63-0 | Molecular Weight | 310.77900 |
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| Density | 1.35g/cm3 | Boiling Point | 494.1ºC at 760 mmHg |
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| Molecular Formula | C14H19ClN4O2 | Melting Point | / |
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| MSDS | / | Flash Point | 252.6ºC |
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Names
| Name | 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydroimidazol-2-yl)methyl]-2-methoxybenzamide |
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| Synonym | More Synonyms |
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Lintopride BiologicalActivity
| Description | Lintopride is a 5HT4 antagonist with moderate 5HT3 antagonist properties. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT ReceptorResearch Areas >>Neurological Disease |
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| Target | 5HT4[1] |
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| In Vitro | Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride[1]. |
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| References | [1]. Delvaux M, et al. The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9. |
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Chemical & Physical Properties
| Density | 1.35g/cm3 |
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| Boiling Point | 494.1ºC at 760 mmHg |
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| Molecular Formula | C14H19ClN4O2 |
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| Molecular Weight | 310.77900 |
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| Flash Point | 252.6ºC |
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| Exact Mass | 310.12000 |
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| PSA | 83.44000 |
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| LogP | 1.92410 |
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| Vapour Pressure | 6.62E-10mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | MJCKISCWHDATBN-UHFFFAOYSA-N |
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| SMILES | CCN1CCN=C1CNC(=O)c1cc(Cl)c(N)cc1OC |
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| Storage condition | 2-8℃ |
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Synonyms
| UNII-C2R0GEU722 |
| Lintopridum [INN-Latin] |
| Lintoprida [INN-Spanish] |
| Lintopridum |
| Lintoprida |
| Lintopride |
