Introduction：Basic information about CAS 79644-90-9|Vebufloxacin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Vebufloxacin |
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| CAS Number | 79644-90-9 | Molecular Weight | 359.39500 |
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| Density | 1.41g/cm3 | Boiling Point | 579.1ºC at 760 mmHg |
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| Molecular Formula | C19H22FN3O3 | Melting Point | / |
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| MSDS | / | Flash Point | 304ºC |
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Names
| Name | Vebufloxacin |
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| Synonym | More Synonyms |
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Vebufloxacin BiologicalActivity
| Description | DM8966 exhibits potent antibacterial activity against gram-positive and -negative bacteria. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
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| Target | Bacteria[1] |
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| In Vitro | A series of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids is synthesized and tested for antibacterial activities. Among them, DM8966 (OPC-7241) exhibits potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, and OPC-7251 shows potent activity characteristically against Propionibacterium acnes[1]. |
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| References | [1]. Ishikawa H, et al. Studies on antibacterial agents. I. Synthesis of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids. Chem Pharm Bull (Tokyo). 1989 Aug;37(8):2103-8. |
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Chemical & Physical Properties
| Density | 1.41g/cm3 |
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| Boiling Point | 579.1ºC at 760 mmHg |
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| Molecular Formula | C19H22FN3O3 |
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| Molecular Weight | 359.39500 |
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| Flash Point | 304ºC |
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| Exact Mass | 359.16500 |
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| PSA | 65.78000 |
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| LogP | 2.10070 |
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| Index of Refraction | 1.661 |
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| InChIKey | JATLJHBAMQKRDH-UHFFFAOYSA-N |
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| SMILES | CC1CCc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 |
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Synonyms
| Benofloxacin |
| 8-(4-methyl-1-piperazinyl)-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid |
| UNII-SXI3MP1G46 |
| 1h,5h-benzo[ij]quinolizine-2-carboxylic acid,9-fluoro-6,7-dihydro-5-methyl-8-(4-methyl-1-piperazinyl)-1-oxo |
| 9-Fluoro-5-methyl-8-(4-methyl-1-piperazinyl)-6,7-dihydro-1-oxo-1H,5H-benzo<ij>quinolizine-2-carboxylic acid |
| DM8966 |
