CAS 3405-88-7|(4-chlorophenylthio)acetic acid

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AG1075000

CHEMICAL NAME :

Acetic acid, ((p-chlorophenyl)thio)-

CAS REGISTRY NUMBER :

3405-88-7

BEILSTEIN REFERENCE NO. :

1871569

LAST UPDATED :

199612

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C8-H7-Cl-O2-S

MOLECULAR WEIGHT :

202.66

WISWESSER LINE NOTATION :

QV1SR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

REFERENCE :

85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946

TYPE OF TEST :

LD - Lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

>400 mg/kg

TOXIC EFFECTS :

Behavioral - sleep Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting

REFERENCE :

85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

1500 mg/kg/5D-I

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Related to Chronic Data - death

REFERENCE :

85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,237,1946