CAS 71989-14-5|FMOC-ASP(OTBU)-OH

Introduction：Basic information about CAS 71989-14-5|FMOC-ASP(OTBU)-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. FMOC-ASP(OTBU)-OH BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	FMOC-ASP(OTBU)-OH
CAS Number	71989-14-5	Molecular Weight	411.448
Density	1.3±0.1 g/cm3	Boiling Point	620.8±55.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₅NO₆	Melting Point	148-150 °C (dec.)
MSDS	ChineseUSA	Flash Point	329.3±31.5 °C

Names

Name	FMOC-L-Aspartic acid β-tert-butyl ester
Synonym	More Synonyms

FMOC-ASP(OTBU)-OH BiologicalActivity

Description	Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Esquivel J B, et al. Chiral HPLC separation of protected amino acids. Journal of liquid chromatography & related technologies, 1998, 21(6): 777-791.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	620.8±55.0 °C at 760 mmHg
Melting Point	148-150 °C (dec.)
Molecular Formula	C₂₃H₂₅NO₆
Molecular Weight	411.448
Flash Point	329.3±31.5 °C
Exact Mass	411.168182
PSA	101.93000
LogP	5.16
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.576
InChIKey	FODJWPHPWBKDON-IBGZPJMESA-N
SMILES	CC(C)(C)OC(=O)CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
Storage condition	2~8°C

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2924299090

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles2

Evaluation of a nonpeptidic ligand for imaging of cholecystokinin 2 receptor-expressing cancers.

J. Nucl. Med. 56(1) , 113-9, (2015)

Tumor-specific targeting ligands were recently exploited to deliver both imaging and therapeutic agents selectively to cancer tissues in vivo. Because the cholecystokinin 2 receptor (CCK2R) is overexp...

Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model.

Sci. Rep. 4 , 6777, (2014)

Amyloid-β (Aβ) is one of the few neuropathological biomarkers associated with transporters of the blood-brain barrier (BBB). Despite the well-characterized clinical indication of decreasing Aβ levels ...

Synonyms

L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester

FMOC-L-Asparticacidbeta-tert-butylester

4-tert-Butyl hydrogen N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-aspartate

(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid

MFCD00037131

FMOC-L-Aspartic acid beta-tert-butyl ester

N-α-FMOC-L-aspartic acid β-tert-butyl ester

Fmoc-L-aspartic acid 4-tert-butyl ester

Fmoc-Asp(OtBu)-OH

EINECS 276-251-7

(2S)-4-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name)

9-fluorenyl-methoxycarbonyl-L-Asp-tert-butyl ester

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