CAS 185517-74-2|TVP1022

Introduction：Basic information about CAS 185517-74-2|TVP1022, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. TVP1022 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	TVP1022
CAS Number	185517-74-2	Molecular Weight	171.23800
Density	/	Boiling Point	/
Molecular Formula	C₁₂H₁₃N	Melting Point	/
MSDS	USA	Flash Point	/
Symbol	GHS07, GHS09	Signal Word	Warning

Names

Name	(1S)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
Synonym	More Synonyms

TVP1022 BiologicalActivity

Description	TVP1022 is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.
Related Catalog	Signaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease
References	[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69. [2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.

Description

TVP1022 is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

Related Catalog

Signaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease

References

[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69.

[2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.

Chemical & Physical Properties

Molecular Formula	C₁₂H₁₃N
Molecular Weight	171.23800
Exact Mass	171.10500
PSA	12.03000
LogP	2.28760
Vapour Pressure	0.000816mmHg at 25°C
InChIKey	RUOKEQAAGRXIBM-LBPRGKRZSA-N
SMILES	C#CCNC1CCc2ccccc21
Storage condition	2-8℃

Safety Information

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H400
Precautionary Statements	P273
RIDADR	UN 3077 9 / PGIII
RTECS	NK8216500

Synonyms

(S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine

(1S)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine (S)-Rasagiline S-(-)-N-Propargyl-1-aminoindan

N-PROPARGYL-1(S)-AMINOINDAN

S-PAI

TVP1022

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