CAS 14985-44-5|8-Bromo-2'-deoxyadenosine

Introduction：Basic information about CAS 14985-44-5|8-Bromo-2'-deoxyadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 8-Bromo-2'-deoxyadenosine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	8-Bromo-2'-deoxyadenosine
CAS Number	14985-44-5	Molecular Weight	330.14
Density	2.3g/cm3	Boiling Point	671ºC at 760mmHg
Molecular Formula	C₁₀H₁₂BrN₅O₃	Melting Point	/
MSDS	/	Flash Point	359.6ºC

Names

Name	8-Bromo-2'-deoxyadenosine
Synonym	More Synonyms

8-Bromo-2'-deoxyadenosine BiologicalActivity

Description	8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

Density	2.3g/cm3
Boiling Point	671ºC at 760mmHg
Molecular Formula	C₁₀H₁₂BrN₅O₃
Molecular Weight	330.14
Flash Point	359.6ºC
Exact Mass	329.01200
PSA	119.31000
LogP	0.39290
Appearance of Characters	Powder \| White to Yellow
Vapour Pressure	6.41E-19mmHg at 25°C
Index of Refraction	1.898
InChIKey	NJBIVXMQFIQOGE-UHFFFAOYSA-N
SMILES	Nc1ncnc2c1nc(Br)n2C1CC(O)C(CO)O1
Water Solubility	Soluble in DMSO or DMF

Safety Information

Hazard Codes	T
Risk Phrases	R24
Safety Phrases	36-45-53

Synonyms

8-Br-dA

(2R,3S,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

8-Bromo-9-(2'-deoxyribofuranosyl)adenine

8-bromo-2'-deoxy-adenosine

8-bromo-deoxyadenosine

8-bromo-2'-deoxydenosine

8-BROMO-2'-DEOXY-D-ADENOSINE

Recommended......