Introduction：Basic information about CAS 13389-03-2|8-Bromo-2'-deoxyguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-Bromo-2'-deoxyguanosine |
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| CAS Number | 13389-03-2 | Molecular Weight | 346.14 |
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| Density | 2.5±0.1 g/cm3 | Boiling Point | 727ºC at 760 mmHg |
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| Molecular Formula | C10H12BrN5O4 | Melting Point | >250ºC dec. |
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| MSDS | / | Flash Point | 393.5ºC |
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Names
| Name | 8-Bromo-2'-deoxyguanosine |
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| Synonym | More Synonyms |
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8-Bromo-2'-deoxyguanosine BiologicalActivity
| Description | 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.5±0.1 g/cm3 |
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| Boiling Point | 727ºC at 760 mmHg |
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| Melting Point | >250ºC dec. |
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| Molecular Formula | C10H12BrN5O4 |
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| Molecular Weight | 346.14 |
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| Flash Point | 393.5ºC |
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| Exact Mass | 345.007263 |
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| PSA | 139.28000 |
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| LogP | -0.02 |
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| Appearance of Characters | Powder | White to Off-white |
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| Vapour Pressure | 3.46E-22mmHg at 25°C |
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| Index of Refraction | 1.941 |
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| Storage condition | -20°C Freezer |
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| Water Solubility | Soluble in dimethyl sulfoxide, warm water and dimethyl formamide. |
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Safety Information
Synonyms
| 2'-Deoxy-8-bromoguanosine |
| C8-bromo-2'-deoxyguanosine |
| Guanosine, 8-bromo-2'-deoxy- |
| 8-Br-dG |
| 8-bromo-2'-deoxyuanosine |
| 8-Bromo-2'-deoxyguanosine |
| 8-Bromo-2'-deoxy-D-guanosine |
| 2-Amino-8-bromo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one |
| 8-bromo2'-deoxyguansine |
