CAS 77-83-8|Ethyl methylphenylglycidate

Introduction：Basic information about CAS 77-83-8|Ethyl methylphenylglycidate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	Ethyl methylphenylglycidate
CAS Number	77-83-8	Molecular Weight	206.238
Density	1.1±0.1 g/cm3	Boiling Point	273.5±30.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₄O₃	Melting Point	/
MSDS	ChineseUSA	Flash Point	109.4±19.2 °C
Symbol	GHS02, GHS07	Signal Word	Warning

Names

Name	Ethyl 3-Methyl-3-Phenylglycidate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	273.5±30.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.238
Flash Point	109.4±19.2 °C
Exact Mass	206.094299
PSA	38.83000
LogP	2.43
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.525
InChIKey	LQKRYVGRPXFFAV-UHFFFAOYSA-N
SMILES	CCOC(=O)C1OC1(C)c1ccccc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MW5250000

CHEMICAL NAME :: Hydrocinnamic acid, alpha,beta-epoxy-beta-methyl-, ethyl ester

CAS REGISTRY NUMBER :: 77-83-8

BEILSTEIN REFERENCE NO. :: 0012299

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C12-H14-O3

MOLECULAR WEIGHT :: 206.26

WISWESSER LINE NOTATION :: T3OTJ B1 BR& CVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5470 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4050 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/2Y-C

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 16 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83193 No. of Facilities: 35 (estimated) No. of Industries: 2 No. of Occupations: 18 No. of Employees: 2735 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83193 No. of Facilities: 1032 (estimated) No. of Industries: 8 No. of Occupations: 17 No. of Employees: 17149 (estimated) No. of Female Employees: 11946 (estimated)

Safety Information

Symbol	GHS02, GHS07
Signal Word	Warning
Hazard Statements	H226-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R10;R36/37/38
Safety Phrases	S16-S26-S36/37/39
RIDADR	UN 1993 3/PG 3
WGK Germany	2
RTECS	MW5250000
HS Code	2918990090

Customs

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

Long-term toxicity study of ethyl methylphenylglycidate (strawberry aldehyde) in the rat.

Food Cosmet. Toxicol. 19(6) , 691-9, (1981)

Synonyms

EINECS 201-061-8

2-Oxiranecarboxylic acid, 3-methyl-3-phenyl-, ethyl ester

3-Methyl-3-phenylglycidic acid ethyl ester

MFCD00022338

ethyl 3-methyl-3-phenyloxirane-2-carboxylate

Strawberry aldehyde

Ethyl methylphenylglycidate

Ethyl 3-methyl-2,3-epoxy-hydrocinamic acid

Ethyl 3-methyl-3-phenylglycidate

Ethyl 3-methyl-3-phenyl-2-oxiranecarboxylate

Ethyl 3-methyl-3-phenyl glycidate

Aldehyde C-16

3-Phenyl-2,3-epoxybutyic acid ethyl ester

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