CAS 82385-42-0|Saccharin sodium hydrate
| Common Name | Saccharin sodium hydrate | ||
|---|---|---|---|
| CAS Number | 82385-42-0 | Molecular Weight | 241.19700 |
| Density | / | Boiling Point | 438.9ºC at 760 mmHg |
| Molecular Formula | C7H8NNaO5S | Melting Point | >300°C |
| MSDS | USA | Flash Point | 219.3ºC |
Names
| Name | Saccharin, sodium salt hydrate |
|---|---|
| Synonym | More Synonyms |
Saccharin sodium hydrate BiologicalActivity
| Description | Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties[1]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
| In Vitro | In vitro, saccharin sodium hydrate (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1]. |
| In Vivo | In vivo, saccharin sodium hydrate (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1]. |
| References | [1]. Sünderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122. |
Chemical & Physical Properties
| Boiling Point | 438.9ºC at 760 mmHg |
|---|---|
| Melting Point | >300°C |
| Molecular Formula | C7H8NNaO5S |
| Molecular Weight | 241.19700 |
| Flash Point | 219.3ºC |
| Exact Mass | 241.00200 |
| PSA | 78.05000 |
| LogP | 1.18550 |
| InChIKey | NPCHGKCOTXZNMS-UHFFFAOYSA-N |
| SMILES | O.O=C1NS(=O)(=O)c2ccccc21.[HH].[Na] |
| Water Solubility | H2O: 1 M at 20 °C, clear, colorless |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | DE4550000 |
Articles6
More Articles| Fructose- and glucose-conditioned preferences in FVB mice: strain differences in post-oral sugar appetition. Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(12) , R1448-57, (2014) Recent studies indicate that, unlike glucose, fructose has little or no post-oral preference conditioning actions in C57BL/6J (B6) mice. The present study determined whether this is also the case for ... | |
| Common-ion effects on the deliquescence lowering of crystalline ingredient blends. Food Chem. 195 , 2-10, (2015) Deliquescence points (RH0, RH0mix) of ionic crystalline food ingredients and blends thereof were determined using water activity and moisture sorption techniques. Measured RH0mix values of ingredient ... | |
| Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice. Chem. Senses 34 , 685-94, (2009) Prior work has shown that sweet taste-deficient T1R3 knockout (KO) mice developed significant sucrose preferences when given long-term sugar versus water tests. The current study investigated the role... |
Synonyms
| MFCD00151213 |
| EINECS 204-886-1 |
| saccharin sodium salt dihydrate |
