CAS 2353-45-9|Fast Green FCF

Introduction：Basic information about CAS 2353-45-9|Fast Green FCF, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Fast Green FCF BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles32
8. Synonyms

Common Name	Fast Green FCF
CAS Number	2353-45-9	Molecular Weight	808.848
Density	/	Boiling Point	/
Molecular Formula	C₃₇H₃₄N₂Na₂O₁₀S₃	Melting Point	290ºC
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS08	Signal Word	Warning

Names

Name	disodium,2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,5-dien-1-ylidene]methyl]-5-hydroxybenzenesulfonate
Synonym	More Synonyms

Fast Green FCF BiologicalActivity

Description	Fast Green FCF is a sea green triarylmethane food dye. Fast Green FCF is used as a quantitative stain for histones at alkaline pH after acid extraction of DNA. It is also used as a protein stain in electrophoresis. Its absorption maximum is at 625 nm.
Related Catalog	Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others

Chemical & Physical Properties

Melting Point	290ºC
Molecular Formula	C₃₇H₃₄N₂Na₂O₁₀S₃
Molecular Weight	808.848
Exact Mass	808.117065
PSA	223.22000
LogP	7.97490
InChIKey	RZSYLLSAWYUBPE-UHFFFAOYSA-L
SMILES	CCN(Cc1cccc(S(=O)(=O)[O-])c1)c1ccc(C(=C2C=CC(=[N+](CC)Cc3cccc(S(=O)(=O)[O-])c3)C=C2)c2ccc(O)cc2S(=O)(=O)[O-])cc1.[Na+].[Na+]
Storage condition	Store at RT.
Water Solubility	H2O: soluble50mg/mL, clear, colorless to faintly yellow

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BQ4425000

CHEMICAL NAME :: Ammonium, ethyl(4-(alpha-(p-(ethyl(m-sulfobenzyl)amino)phenyl)- 4-hydroxy-3-sulfobenz ylidene)- 2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, disodium salt

CAS REGISTRY NUMBER :: 2353-45-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C37-H36-N2-O10-S3.2Na

MOLECULAR WEIGHT :: 810.91

WISWESSER LINE NOTATION :: L6Y DYJ AUYR DQ CSWQ&R DN2&1R CSWQ&& DUK2&1R CSWQ &Q &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5925 mg/kg/48W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 2 gm/L

REFERENCE :: GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,187,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,187,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3843 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 221 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3843 No. of Facilities: 774 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 9107 (estimated) No. of Female Employees: 6209 (estimated)

Safety Information

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H341
Precautionary Statements	P281
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22;R40
Safety Phrases	S25-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BQ4425000
HS Code	32041900

Customs

HS Code	32041900

Articles32

Three puncture sites used for in utero electroporation show no significantly different negative impacts during gene transfer into the embryonic mouse brain.

Neurosci. Lett. 578 , 176-81, (2014)

Although various ways to manipulate genes in vivo exist, in utero electroporation is a widely used technique, especially in the field of neural development due to its many advantages. In this study, w...

Differences in copper bioaccumulation and biological responses in three Mytilus species.

Aquat. Toxicol. 160 , 1-12, (2015)

Mytilus species are important organisms in marine systems being highly abundant and widely distributed along the coast of Europe and worldwide. They are typically used in biological effects studies an...

Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes.

PLoS ONE 6(7) , e22801, (2011)

Doxorubicin (Dox) is an anthracycline used to effectively treat several forms of cancer. Unfortunately, the use of Dox is limited due to its association with cardiovascular complications which are man...

Synonyms

MFCD00013053

C Green no. 3

Food green 3

C.I. Food Green 3

Fast green FCF

N-Ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfobenzenemethanaminium Hydroxide Inner Salt Disodium Salt

benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)

Disodium 2-[(Z)-{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}{(4Z)-4-[ethyl(3-sulfonatobenzyl)iminio]-2,5-cyclohexadien-1-ylidene}methyl]-5-hydroxybenzenesulfonate

FDC Green No. 3

1724 Green

Food Green No. 3

benzenemethanaminium, N-ethyl-N-[(1Z,4Z)-4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)

FD and C green 3

EINECS 219-091-5

Benzenemethanaminium, N-ethyl-N-[(1E,4E)-4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2)

Solid Green FCF

Fast Green FCF,certified

Disodium 2-[(E)-{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}{(4E)-4-[ethyl(3-sulfonatobenzyl)iminio]-2,5-cyclohexadien-1-ylidene}methyl]-5-hydroxybenzenesulfonate

disodium salt of fast green FCF

Disodium 2-[(E)-{4-[ethyl(3-sulfonatobenzyl)amino]phenyl}{(4E)-4-[ethyl(3-sulfonatobenzyl)iminio]cyclohexa-2,5-dien-1-ylidene}methyl]-5-hydroxybenzenesulfonate

Disodium 2-({4-[ethyl(3-sulfonatobenzyl)amino]phenyl}{4-[ethyl(3-sulfonatobenzyl)iminio]cyclohexa-2,5-dien-1-ylidene}methyl)-5-hydroxybenzenesulfonate

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