Introduction：Basic information about CAS 41303-74-6|N-Desmethyl Galanthamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Desmethyl Galanthamine |
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| CAS Number | 41303-74-6 | Molecular Weight | 273.32700 |
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| Density | 1.309g/cm3 | Boiling Point | 457.923ºC at 760 mmHg |
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| Molecular Formula | C16H19NO3 | Melting Point | 142-145ºC |
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| MSDS | / | Flash Point | 230.744ºC |
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Names
| Name | N-Desmethyl Galanthamine |
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| Synonym | More Synonyms |
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N-Desmethyl Galanthamine BiologicalActivity
| Description | N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668. [2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86. |
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Chemical & Physical Properties
| Density | 1.309g/cm3 |
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| Boiling Point | 457.923ºC at 760 mmHg |
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| Melting Point | 142-145ºC |
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| Molecular Formula | C16H19NO3 |
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| Molecular Weight | 273.32700 |
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| Flash Point | 230.744ºC |
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| Exact Mass | 273.13600 |
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| PSA | 50.72000 |
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| LogP | 1.83690 |
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| Index of Refraction | 1.642 |
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| InChIKey | AIXQQSTVOSFSMO-RBOXIYTFSA-N |
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| SMILES | COc1ccc2c3c1OC1CC(O)C=CC31CCNC2 |
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Safety Information
Synonyms
| N-Norgalanthamine |
| N-Demethylgalantamine |
| Norgalantamine |
| N-desmethyl galantamine |
| UNII-2BPQ4IVQ21 |
