CAS 17119-15-2|3-Hydroxymandelic Acid
| Common Name | 3-Hydroxymandelic Acid | ||
|---|---|---|---|
| CAS Number | 17119-15-2 | Molecular Weight | 168.14700 |
| Density | 1.48g/cm3 | Boiling Point | 424.3ºC at 760mmHg |
| Molecular Formula | C8H8O4 | Melting Point | 128-132ºC |
| MSDS | ChineseUSA | Flash Point | 224.5ºC |
Names
| Name | 3-hydroxymandelic acid |
|---|---|
| Synonym | More Synonyms |
3-Hydroxymandelic Acid BiologicalActivity
| Description | 3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist. |
|---|---|
| Related Catalog | Research Areas >>Others |
| Target | Human Endogenous Metabolite |
| In Vitro | Phenylephrine, an alpha-receptor agonist is metabolized to m-hydroxyphenylglycol (MHPG) and m-hydroxymandelic acid (MHMA) in the human body[1]. It is probable that urinary MHMA originates from m-octopamine or m-synephrine (Phenylephrine) or both[1]. |
| References | [1]. Gumbhir K, et al. Determination of m-hydroxymandelic acid, m-hydroxyphenylglycol and their conjugates in human plasma using liquid chromatography with electrochemical detection. J Pharm Biomed Anal. 1994 Jul;12(7):943-9. [2]. Crowley JR, et al. Normal excretion of m-hydroxymandelic acid in hypertensive patients. Clin Chim Acta. 1981 Jan 22;109(2):125-31. |
Chemical & Physical Properties
| Density | 1.48g/cm3 |
|---|---|
| Boiling Point | 424.3ºC at 760mmHg |
| Melting Point | 128-132ºC |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.14700 |
| Flash Point | 224.5ºC |
| Exact Mass | 168.04200 |
| PSA | 77.76000 |
| LogP | 0.51020 |
| Vapour Pressure | 5.91E-08mmHg at 25°C |
| Index of Refraction | 1.637 |
| InChIKey | OLSDAJRAVOVKLG-UHFFFAOYSA-N |
| SMILES | O=C(O)C(O)c1cccc(O)c1 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918290000 |
Customs
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
Articles28
More Articles| Improving the serum D-xylose test for the identification of patients with small intestinal malabsorption. J. Clin. Gastroenterol. 33(1) , 36-40, (2001) D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain.We pr... | |
| Plasma amino acid profile on nocturnal hemodialysis. Blood Purif. 18(2) , 97-102, (2000) The purpose of this study was to examine the effect of nocturnal hemodialysis (NHD) on serum amino acid (AA) profile.In a cross-over trial, we studied the AA profile in 11 patients who were switched f... | |
| Plasma pteridine concentrations in patients with chronic renal failure. Nephrol. Dial. Transplant. 17(6) , 1032-6, (2002) Pteridine metabolism is impaired in the uraemic state. This may affect cardiovascular function and contribute to malnutrition. We wished to clarify further the impact of impaired pteridine metabolism.... |
Synonyms
| 3-Hydroxy-mandelsaeure |
| 3-Hydroxymandelic Acid |
| EINECS 241-182-3 |
| M-hydroxymandelate |
| MFCD00042723 |
| m-Hydroxymandelic acid |
| MHMA |
| 3-Hydroxyphenylglycolic acid |
| 2-hydroxy-2-(3-hydroxyphenyl)acetic acid |
