CAS 108656-33-3|Florfenicol amine hydrochloride

Introduction：Basic information about CAS 108656-33-3|Florfenicol amine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Florfenicol amine hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Florfenicol amine hydrochloride
CAS Number	108656-33-3	Molecular Weight	283.75
Density	/	Boiling Point	/
Molecular Formula	C₁₀H₁₅ClFNO₃S	Melting Point	162-164ºC
MSDS	/	Flash Point	/

Names

Name	florfenicol amine, hydrochloride
Synonym	More Synonyms

Florfenicol amine hydrochloride BiologicalActivity

Description	Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases[1][2].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
References	[1]. B-K Park, et al. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus). J Vet Pharmacol Ther. 2006 Feb;29(1):37-40. [2]. Anadón A, et al. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 2008 Nov 26;56(22):11049-56.

Description

Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases[1][2].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial

References

[1]. B-K Park, et al. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus). J Vet Pharmacol Ther. 2006 Feb;29(1):37-40.

[2]. Anadón A, et al. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 2008 Nov 26;56(22):11049-56.

Chemical & Physical Properties

Melting Point	162-164ºC
Molecular Formula	C₁₀H₁₅ClFNO₃S
Molecular Weight	283.75
Exact Mass	283.04500
PSA	88.77000
LogP	3.00340
InChIKey	HWPBPTAOXVIKGI-DHTOPLTISA-N
SMILES	CS(=O)(=O)c1ccc(C(O)C(N)CF)cc1.Cl

Synonyms

Florfenicol Amine Hydrochloride

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