CAS 88404-14-2|6,7-Dihydroxycoumarin-4-acetic Acid

Introduction：Basic information about CAS 88404-14-2|6,7-Dihydroxycoumarin-4-acetic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 6,7-Dihydroxycoumarin-4-acetic Acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	6,7-Dihydroxycoumarin-4-acetic Acid
CAS Number	88404-14-2	Molecular Weight	236.17800
Density	/	Boiling Point	/
Molecular Formula	C₁₁H₈O₆	Melting Point	230ºC
MSDS	/	Flash Point	/

Names

Name	6,7-Dihydroxycoumarin-4-acetic Acid
Synonym	More Synonyms

6,7-Dihydroxycoumarin-4-acetic Acid BiologicalActivity

Description	6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation[1].
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>Aldose ReductaseResearch Areas >>Metabolic Disease
References	[1]. Kato A, et al. 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3.

Chemical & Physical Properties

Melting Point	230ºC
Molecular Formula	C₁₁H₈O₆
Molecular Weight	236.17800
Exact Mass	236.03200
PSA	107.97000
LogP	0.83130
InChIKey	VZBNZFYHLQRFPS-UHFFFAOYSA-N
SMILES	O=C(O)Cc1cc(=O)oc2cc(O)c(O)cc12

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36

Synonyms

2-(6,7-dihydroxy-2-oxochromen-4-yl)acetic acid

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