Introduction：Basic information about CAS 28585-51-5|2-Thiothymidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Thiothymidine |
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| CAS Number | 28585-51-5 | Molecular Weight | 258.29 |
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| Density | 1.52 g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H14N2O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one |
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| Synonym | More Synonyms |
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2-Thiothymidine BiologicalActivity
| Description | 2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.52 g/cm3 |
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| Molecular Formula | C10H14N2O4S |
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| Molecular Weight | 258.29 |
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| Exact Mass | 258.06700 |
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| PSA | 119.57000 |
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| Index of Refraction | 1.672 |
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| InChIKey | PISWNSOQFZRVJK-XLPZGREQSA-N |
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| SMILES | Cc1cn(C2CC(O)C(CO)O2)c(=S)[nH]c1=O |
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Synonyms
| Thymidine,2-thio |
| 2-Thiothymidin |
| 2-thiothymidine |
| 2-Thio-desoxythymidin |
