Introduction：Basic information about CAS 106449-56-3|2'-Deoxyisoguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxyisoguanosine |
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| CAS Number | 106449-56-3 | Molecular Weight | 267.24 |
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| Density | 2.08g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H13N5O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one |
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| Synonym | More Synonyms |
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2'-Deoxyisoguanosine BiologicalActivity
| Description | 2'-Deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.08g/cm3 |
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| Molecular Formula | C10H13N5O4 |
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| Molecular Weight | 267.24 |
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| Exact Mass | 267.09700 |
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| PSA | 134.99000 |
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| Index of Refraction | 1.907 |
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| InChIKey | SWFIFWZFCNRPBN-KVQBGUIXSA-N |
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| SMILES | Nc1[nH]c(=O)nc2c1ncn2C1CC(O)C(CO)O1 |
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Synonyms
| Adenosine,1,2-dihydro-2'-deoxy-2-oxo |
| 2-Hydroxydeoxyadenosine |
| 1,2-Dihydro-2'-deoxy-2-oxoadenosine |
| Deoxyisoguanosine |
| 2'-Deoxyisoguanosine |
