CAS 6525-53-7|Dimethyl Glutamate
Introduction：Basic information about CAS 6525-53-7|Dimethyl Glutamate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dimethyl Glutamate | ||
|---|---|---|---|
| CAS Number | 6525-53-7 | Molecular Weight | 175.18200 |
| Density | 1.129 g/cm3 | Boiling Point | 224.292ºC at 760 mmHg |
| Molecular Formula | C7H13NO4 | Melting Point | / |
| MSDS | / | Flash Point | 76.674ºC |
Names
| Name | (S)-Dimethyl 2-aminopentanedioate |
|---|---|
| Synonym | More Synonyms |
Dimethyl Glutamate BiologicalActivity
| Description | Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism[1][2][3][4]. |
|---|---|
| Related Catalog | Research Areas >>InfectionResearch Areas >>Metabolic DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium ChannelSignaling Pathways >>Anti-infection >>Bacterial |
| Target | KATP channel[4] |
| References | [1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2. [2]. Sener A, et al. Insulinotropic action of glutamic acid dimethyl ester. American Journal of Physiology-Endocrinology and Metabolism, 1994, 267(4): E573-E584. [3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5. [4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4. |
Chemical & Physical Properties
| Density | 1.129 g/cm3 |
|---|---|
| Boiling Point | 224.292ºC at 760 mmHg |
| Molecular Formula | C7H13NO4 |
| Molecular Weight | 175.18200 |
| Flash Point | 76.674ºC |
| Exact Mass | 175.08400 |
| PSA | 78.62000 |
| LogP | 0.14020 |
| InChIKey | YEJSPQZHMWGIGP-YFKPBYRVSA-N |
| SMILES | COC(=O)CCC(N)C(=O)OC |
Safety Information
| Hazard Codes | Xi |
|---|
Synonyms
| dimethyl L-glutamate |
| L-glutamic acid a,g-dimethyl ester |
| glutamic acid dimethyl ester |
| L-glutamic acid dimethyl ester |
| Dimethyl Glutamate |
| Einecs 229-414-1 |
