CAS 64987-85-5|N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Introduction：Basic information about CAS 64987-85-5|N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
References
[1]. Guo Y, et al. Potent antigen-specific immune response induced by infusion of spleen cells coupled with succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate (SMCC) conjugated antigens. Int Immunopharmacol. 2016 Feb;31:158-68.
Chemical & Physical Properties
Density
1.4±0.1 g/cm3
Boiling Point
501.7±42.0 °C at 760 mmHg
Melting Point
180-182 °C(lit.)
Molecular Formula
C16H18N2O6
Molecular Weight
334.324
Flash Point
257.2±27.9 °C
Exact Mass
334.116486
PSA
101.06000
LogP
-0.39
Vapour Pressure
0.0±1.3 mmHg at 25°C
Index of Refraction
1.598
InChIKey
JJAHTWIKCUJRDK-UHFFFAOYSA-N
SMILES
O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1
Storage condition
2-8°C
Water Solubility
chloroform: 50 mg/mL
Safety Information
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xi: Irritant;
Risk Phrases
R36/37/38
Safety Phrases
S26-S36
RIDADR
NONH for all modes of transport
WGK Germany
3
HS Code
2925190090
Customs
HS Code
2925190090
Summary
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles75
More Articles
A Humanized Anti-CD22-Onconase Antibody-Drug Conjugate Mediates Highly Potent Destruction of Targeted Tumor Cells.
J. Immunol. Res. 2015 , 561814, (2015)
Antibody-drug conjugates (ADCs) have evolved as a new class of potent cancer therapeutics. We here report on the development of ADCs with specificity for the B-cell lineage specific (surface) antigen ...
Solid formulations by a nanocrystal approach: critical process parameters regarding scale-ability of nanocrystals for tableting applications.
Int. J. Pharm. 485 , 77-86, (2015)
Nanocrystallization is among the foremost drug delivery platform approaches for the commercial development of poorly soluble drugs. There exists an urge to enable a universal shift of the production o...
An NIR-triggered and thermally responsive drug delivery platform through DNA/copper sulfide gates.
Nanoscale 7 , 12614-24, (2015)
Nanomaterials for effective drug delivery require zero pre-release and on-demand release of therapeutic drugs. In this work we demonstrate a novel drug delivery system composed of a mesoporous silica ...
