Introduction：Basic information about CAS 65886-71-7|1b-D-Arabinofuranosyl-5-azacytosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1b-D-Arabinofuranosyl-5-azacytosine |
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| CAS Number | 65886-71-7 | Molecular Weight | 244.205 |
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| Density | 2.1±0.1 g/cm3 | Boiling Point | 534.5±60.0 °C at 760 mmHg |
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| Molecular Formula | C8H12N4O5 | Melting Point | 228-230ºC (decomposes) |
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| MSDS | / | Flash Point | 277.0±32.9 °C |
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Names
| Name | 1-.β.-D-Arabinofuranosyl-5-azacytosine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 2.1±0.1 g/cm3 |
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| Boiling Point | 534.5±60.0 °C at 760 mmHg |
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| Melting Point | 228-230ºC (decomposes) |
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| Molecular Formula | C8H12N4O5 |
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| Molecular Weight | 244.205 |
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| Flash Point | 277.0±32.9 °C |
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| Exact Mass | 244.080765 |
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| PSA | 143.72000 |
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| LogP | -1.99 |
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| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
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| Index of Refraction | 1.823 |
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| InChIKey | NMUSYJAQQFHJEW-ARQDHWQXSA-N |
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| SMILES | Nc1ncn(C2OC(CO)C(O)C2O)c(=O)n1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XZ2854400
- CHEMICAL NAME :
- s-Triazin-2(1H)-one, 4-amino-1-beta-D-arabinofuranosyl-
- CAS REGISTRY NUMBER :
- 65886-71-7
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H12-N4-O5
- MOLECULAR WEIGHT :
- 244.24
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 1557 ug/kg/72H-C
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - agranulocytosis
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 2 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 24,297,1983
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Synonyms
| 4-Amino-1-(β-D-arabinofuranosyl)-1,3,5-triazin-2(1H)-one |
| 1b-D-Arabinofuranosyl-5-azacytosine |
| 4-Amino-1b-D-arabinofuranosyl-s-triazin-2(1H)-one |
| Fazarabine |
| 5-azacytosine arabinoside |
| ara-AC |
| 1-β-D-Arabinofuranosyl-5-azacytosine |
| 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one |
| 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-arabinofuranosyl- |
| 5-azaaracytidine |
