CAS 6375-16-2|N-(3-Amino-4-methylphenyl)acetamide

Introduction：Basic information about CAS 6375-16-2|N-(3-Amino-4-methylphenyl)acetamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Articles3
6. Synonyms

Common Name	N-(3-Amino-4-methylphenyl)acetamide
CAS Number	6375-16-2	Molecular Weight	164.20400
Density	1.109g/cm3	Boiling Point	645.4ºC at 760 mmHg
Molecular Formula	C₉H₁₂N₂O	Melting Point	/
MSDS	ChineseUSA	Flash Point	213.5ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	N-(3-Amino-4-methylphenyl)acetamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.109g/cm3
Boiling Point	645.4ºC at 760 mmHg
Molecular Formula	C₉H₁₂N₂O
Molecular Weight	164.20400
Flash Point	213.5ºC
Exact Mass	164.09500
PSA	55.12000
LogP	2.18980
Index of Refraction	1.605
InChIKey	RBQWGHBZCHFUQU-UHFFFAOYSA-N
SMILES	CC(=O)Nc1ccc(C)c(N)c1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AD8580000

CHEMICAL NAME :: Acetanilide, 3'-amino-4'-methyl-

CAS REGISTRY NUMBER :: 6375-16-2

BEILSTEIN REFERENCE NO. :: 2804114

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H12-N2-O

MOLECULAR WEIGHT :: 164.23

WISWESSER LINE NOTATION :: ZR B1 EMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 400 ug/plate

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 33,4556,1985

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport
RTECS	AD8580000

Articles3

Evidence for an acetoxyarylamine as the ultimate mutagenic reactive intermediate of the carcinogenic aromatic amine 2,4-diaminotoluene.

Mutat. Res. 242(2) , 101-10, (1990)

2,4-Diaminotoluene (2,4-DAT) is a mutagenic and hepatocarcinogenic aromatic amine, requiring metabolic activation. We have found that the mutagenic potency of 2,4-DAT in Salmonella TA98 is similar whe...

Comparison of the metabolism of 2,4-toluenediamine in rats and mice.

J. Environ. Pathol. Toxicol. 3(1-2) , 149-66, (1979)

The excretion, distribution, and metabolism of 2,4-toluenediamine (TDA) have been compared in rats and mice. The elimination of TDA metabolites into urine was faster and more complete in mice than in ...

Gas chromatographic/tandem mass spectrometric identification and quantitation of metabolic 4-acetyltoluene-2,4-diamine from the F344 rat.

Biol. Mass Spectrom. 22(3) , 194-200, (1993)

2,4-Toluenediamine (TDA) and 2,4-toluenediisocyanate (TDI) are metabolized in the Fischer 344 rat to monoacetyl-2,4-toluenediamine (Ac-TDA) and diacetyl-2,4-toluenediamine (Ac2-TDA). A gas chromatogra...

Synonyms

4-acetylamino-2-aminotoluene

5-Acetylamino-o-toluidine

3'-Amino-p-acetotoluidide

N-(3-amino-4-methylphenyl)acetamide(SALTDATA: FREE)

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