CAS 923-16-0|H-D-Ala-D-Ala-OH
| Common Name | H-D-Ala-D-Ala-OH | ||
|---|---|---|---|
| CAS Number | 923-16-0 | Molecular Weight | 160.17100 |
| Density | 1.208 g/cm3 | Boiling Point | 402.6ºC at 760 mmHg |
| Molecular Formula | C6H12N2O3 | Melting Point | 286 - 288ºC |
| MSDS | ChineseUSA | Flash Point | 197.3ºC |
Names
| Name | D-alanyl-D-alanine |
|---|---|
| Synonym | More Synonyms |
H-D-Ala-D-Ala-OH BiologicalActivity
| Description | D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. D-Ala-D-Ala is a bacterial endogenous metabolite[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| Target | Microbial Metabolite |
| References | [1]. Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106. [2]. Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80. |
Chemical & Physical Properties
| Density | 1.208 g/cm3 |
|---|---|
| Boiling Point | 402.6ºC at 760 mmHg |
| Melting Point | 286 - 288ºC |
| Molecular Formula | C6H12N2O3 |
| Molecular Weight | 160.17100 |
| Flash Point | 197.3ºC |
| Exact Mass | 160.08500 |
| PSA | 92.42000 |
| LogP | 0.01410 |
| InChIKey | DEFJQIDDEAULHB-QWWZWVQMSA-N |
| SMILES | CC(N)C(=O)NC(C)C(=O)O |
| Storage condition | −20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles46
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| Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727. Antimicrob. Agents Chemother. 58(9) , 5191-201, (2014) Glycopeptides and β-lactams inhibit bacterial peptidoglycan synthesis in Gram-positive bacteria; resistance to these antibiotics is studied intensively in enterococci and staphylococci because of thei... | |
| Bond dissociation of the dipeptide dialanine and its derivative alanine anhydride induced by low energy electrons. J. Chem. Phys. 134(5) , 054305, (2011) Dissociative electron attachment to dialanine and alanine anhydride has been studied in the gas phase utilizing a double focusing two sector field mass spectrometer. We show that low-energy electrons ... |
Synonyms
| D-ALANYL-D-ALANINE |
| MFCD00066038 |
| (R)-2-((R)-2-Aminopropanamido)propanoic acid |
| H-D-ALA-D-ALA-OH |
| D-ALA-D-ALA |
| D-Ala-D-Ala-OH |
