CAS 33675-83-1|(2H5)Acetamide

Introduction：Basic information about CAS 33675-83-1|(2H5)Acetamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (2H5)Acetamide BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(2H5)Acetamide
CAS Number	33675-83-1	Molecular Weight	64.098
Density	0.9±0.1 g/cm3	Boiling Point	221.1±0.0 °C at 760 mmHg
Molecular Formula	C₂D₅NO	Melting Point	78-80ºC(lit.)
MSDS	ChineseUSA	Flash Point	90.1±18.4 °C

Names

Name	N,N,2,2,2-pentadeuterioacetamide
Synonym	More Synonyms

(2H5)Acetamide BiologicalActivity

Description	Acetamide-d5 is the deuterium labeled Acetamide[1]. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[2][3].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Acetamide. IARC Monogr Eval Carcinog Risks Hum. 1999;71 Pt 3:1211-21. [3]. Moore MM, et, al. The food contaminant acetamide is not an in vivo clastogen, aneugen, or mutagen in rodent hematopoietic tissue. Regul Toxicol Pharmacol. 2019 Nov108:104451.

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	221.1±0.0 °C at 760 mmHg
Melting Point	78-80ºC(lit.)
Molecular Formula	C₂D₅NO
Molecular Weight	64.098
Flash Point	90.1±18.4 °C
Exact Mass	64.068497
PSA	43.09000
LogP	-1.23
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.393
InChIKey	DLFVBJFMPXGRIB-OMNVKBNWSA-N
SMILES	CC(N)=O

Safety Information

Hazard Codes	Xn: Harmful;
Risk Phrases	R40
Safety Phrases	36/37
RIDADR	UN 3077 9 / PGIII

Synonyms

Acetamide-d

(H)Acetamide

Acetamide-d5

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