CAS 347840-08-8|2-Methylsuccinic acid-d6
Introduction：Basic information about CAS 347840-08-8|2-Methylsuccinic acid-d6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Methylsuccinic acid-d6 | ||
|---|---|---|---|
| CAS Number | 347840-08-8 | Molecular Weight | 138.15200 |
| Density | / | Boiling Point | / |
| Molecular Formula | C5H2D6O4 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | 2-methyl-d3-succinic-2,3,3-d3 acid |
|---|
2-Methylsuccinic acid-d6 BiologicalActivity
| Description | 2-Methylsuccinic acid-d6 is the deuterium labeled 2-Methylsuccinic acid[1]. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy[2][3]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50. [3]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul47(7):836-9. |
Chemical & Physical Properties
| Molecular Formula | C5H2D6O4 |
|---|---|
| Molecular Weight | 138.15200 |
| Exact Mass | 138.08000 |
| PSA | 74.60000 |
| LogP | 0.18180 |
| InChIKey | WXUAQHNMJWJLTG-LIDOUZCJSA-N |
| SMILES | CC(CC(=O)O)C(=O)O |
