CAS 347841-44-5|(2H9)-9H-Fluoren-2-(2H2)amine
Introduction：Basic information about CAS 347841-44-5|(2H9)-9H-Fluoren-2-(2H2)amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (2H9)-9H-Fluoren-2-(2H2)amine | ||
|---|---|---|---|
| CAS Number | 347841-44-5 | Molecular Weight | 192.301 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 379.3±21.0 °C at 760 mmHg |
| Molecular Formula | C13D11N | Melting Point | / |
| MSDS | / | Flash Point | 204.8±17.4 °C |
Names
| Name | 2-aminofluorene-d11 |
|---|---|
| Synonym | More Synonyms |
(2H9)-9H-Fluoren-2-(2H2)amine BiologicalActivity
| Description | 2-Aminofluorene-d11 is the deuterium labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4]. |
|---|---|
| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Heflich RH, et al. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat Res. 1994 Oct;318(2):73-114. ; ; [3]. Kim BS, et al. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug Chem Toxicol. 1989 Sep-Dec;12(3-4):297-311. [4]. Levy GN, et al. 2-Aminofluorene-DNA adduct formation in acetylator congenic mouse lines. Carcinogenesis. 1989 Apr;10(4):705-9. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 379.3±21.0 °C at 760 mmHg |
| Molecular Formula | C13D11N |
| Molecular Weight | 192.301 |
| Flash Point | 204.8±17.4 °C |
| Exact Mass | 192.158188 |
| PSA | 26.02000 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.697 |
| InChIKey | CFRFHWQYWJMEJN-DCWZJRGXSA-N |
| SMILES | Nc1ccc2c(c1)Cc1ccccc1-2 |
Synonyms
| 9H-Fluoren-d-2-amine-d |
| (H)-9H-Fluoren-2-(H)amine |
