Introduction：Basic information about CAS 194022-51-0|Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid) |
|---|
| CAS Number | 194022-51-0 | Molecular Weight | 543.567 |
|---|
| Density | 1.3±0.1 g/cm3 | Boiling Point | 996.6±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C23H37N5O10 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 556.5±34.3 °C |
|---|
Names
| Name | (3S)-3-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Cell Cycle/DNA Damage >>Casein KinaseSignaling Pathways >>Stem Cell/Wnt >>Casein Kinase |
|---|
| Target | caspase-2/3[1] |
|---|
| References | [1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 996.6±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C23H37N5O10 |
|---|
| Molecular Weight | 543.567 |
|---|
| Flash Point | 556.5±34.3 °C |
|---|
| Exact Mass | 543.254028 |
|---|
| PSA | 237.17000 |
|---|
| LogP | 0.42 |
|---|
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.520 |
|---|
| InChIKey | OOGHGBCRVSBUHH-GOYXDOSHSA-N |
|---|
| SMILES | CC(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(C)C(=O)NC(C=O)CC(=O)O)C(C)C)C(C)C |
|---|
Safety Information
Synonyms
| N-Acetyl-Val-Asp-Val-Ala-Asp-CHO |
| L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]- |
| Ac-VDVAD-CHO |
| N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide |
| 2h65 |
