Introduction：Basic information about CAS 484-43-5|5-Valine-angiotensin I, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2].
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Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
In Vitro
5-Valine-angiotensin I shows myotropic effect (muscle contraction) on isolated rat colon after nonspecific desensitization of receptors with acetylcholine[2].
Because of the importance of the renin-angiotensin system in the pathophysiology of hypertension and in mediating associated alterations in renal function, angiotensin II (Ang II) AT1 receptor blocker...
Purification and identification of endogenous anti-opioid substances from bovine brain.
Two fractions with high potency for reversing the inhibitory effect of Met-enkephalin on the electrically induced contractility of guinea-pig ileum have been purified from bovine brain extract. Unexpe...
Determination of renin activity in human plasma by column-switching high-performance liquid chromatography with fluorescence detection. Miyazaki T, Kai M, Ohkura Y.
